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5-(2-Hydroxyethyl)-3-(4-hydroxy-2-methylpyrimidin-5-ylmethyl)-4-methylthiazolium chloride, also known as hydroxythiamine (HT), is a potent vitamin B1 antagonist that inhibits thiamine diphosphate-dependent enzymes in most tissues but cannot cross the blood-brain barrier, limiting its effects on the brain. Its derivatives, such as HT esters, have been developed to enhance nerve tissue penetration, resulting in milder systemic antivitamin activity while exerting stronger inhibition of thiamine-dependent enzymes in the brain. These properties make HT and its analogs valuable tools for studying thiamine metabolism and potential therapeutic applications.

582-36-5

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582-36-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 582-36-5 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,8 and 2 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 582-36:
(5*5)+(4*8)+(3*2)+(2*3)+(1*6)=75
75 % 10 = 5
So 582-36-5 is a valid CAS Registry Number.
InChI:InChI=1/C12H15N3O2S.ClH/c1-8-11(3-4-16)18-7-15(8)6-10-5-13-9(2)14-12(10)17;/h5,7,16H,3-4,6H2,1-2H3;1H

582-36-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name oxythiamine chloride

1.2 Other means of identification

Product number -
Other names Oxythiamine chloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:582-36-5 SDS

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