5820-23-5

Upstream product

• 1458-98-6 2-methyl-3-bromo-1-propene 
• 106-48-9 4-chloro-phenol 
• 563-47-3 3-Chloro-2-methylpropene 

Downstream Products

• 107970-05-8 1-((E)-3-Bromo-2-methyl-allyloxy)-4-chloro-benzene 
• 1280721-74-5 C₂₀H₁₆ClNO₂ 
• 5894-97-3 3-(4-chloro-phenoxy)-2,2-dimethyl-cyclopropanecarboxylic acid ethyl ester 
• 5842-37-5 3-(4-chlorophenoxy)-2,2-dimethylcyclopropanecarboxylic acid 
• 88283-54-9 C₁₀H₁₁Cl₃OS 
• 107970-11-6 1-Chloro-4-(2,3-dibromo-2-methyl-propoxy)-benzene 
• 63834-70-8 3-(4-chloro-phenoxy)-2-methyl-propane-1,2-diol 
• 5820-30-4 1-chloro-4-((2-methylprop-1-en-1-yl)oxy)benzene 

Relevant academic research and scientific papers

Development and Mechanistic Study of Quinoline-Directed Acyl C-O Bond Activation and Alkene Oxyacylation Reactions

The intramolecular addition of both an alkoxy and acyl substituent across an alkene, oxyacylation of alkenes, using rhodium catalyzed C-O bond activation of an 8-quinolinyl ester is described. Our unsuccessful attempts at intramolecular carboacylation of ketones via C-C bond activation ultimately informed our choice to pursue and develop the intramolecular oxyacylation of alkenes via quinoline-directed C-O bond activation. We provide a full account of our catalyst discovery, substrate scope, and mechanistic experiments for quinoline-directed alkene oxyacylation.

Pd-Catalyzed regioselective hydroesterification of 2-allylphenols to seven-membered lactones without external CO gas

Effective Pd-catalyzed regioselective hydroesterification of 2-allylphenols with phenyl formate is described. A variety of seven-membered lactones can be obtained in good yields under mild conditions without the use of toxic CO gas.

Insertion of an Alkene into an ester: Intramolecular oxyacylation reaction of alkenes through acyl C-O bond activation

Atom economy and esters: compatible now! The first catalytic insertion of a C-C bond into an acyl C-O bond was achieved using rhodium catalysts (see scheme). The products are β-alkoxy ketones with a fully substituted carbon center. Quinoline chelating groups were employed to stabilize the Rh-alkoxide intermediate.

Ether substituted cyclopropanecarboxylic acids and esters

Novel esters of ether and thioether substituted cyclopropanecarboxylic acids, synthesis thereof, and intermediates therefor, such esters being useful as pesticides.