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[3-[bis(2-chloroethyl)amino]-5-(carbamoylamino)phenyl]urea, also known as chlorozotocin, is a synthetic alkylating agent derived from urea. It possesses alkylating and carbamoylating functional groups, which enable it to exert cytotoxic effects by damaging the DNA of cancer cells. Chlorozotocin is a promising pharmaceutical candidate for various applications in the field of oncology.

58200-04-7

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58200-04-7 Usage

Uses

Used in Anticancer Applications:
Chlorozotocin is used as an anticancer agent for the treatment of various types of cancer, including pancreatic neuroendocrine tumors and advanced carcinoid tumors. It modulates several oncological signaling pathways, exerting inhibitory effects on tumor growth and progression. Additionally, it demonstrates synergistic anticancer effects when combined with conventional chemotherapeutic drugs, enhancing chemo-sensitivity and efficacy in resistant cases.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, chlorozotocin is used as a potential chemotherapy agent for the development of new cancer treatments. Its unique mechanism of action, which involves damaging the DNA of cancer cells, makes it a valuable compound for research and development in the fight against cancer.
Used in Clinical Trials:
Chlorozotocin is also used in clinical trials to evaluate its safety, efficacy, and potential side effects when used in combination with other cancer treatments. These trials help to determine the optimal dosage and administration methods for the drug, as well as its overall effectiveness in treating specific types of cancer.
Overall, [3-[bis(2-chloroethyl)amino]-5-(carbamoylamino)phenyl]urea, or chlorozotocin, is a versatile and promising compound in the field of oncology, with various applications in cancer treatment, pharmaceutical research, and clinical trials.

Check Digit Verification of cas no

The CAS Registry Mumber 58200-04-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,8,2,0 and 0 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 58200-04:
(7*5)+(6*8)+(5*2)+(4*0)+(3*0)+(2*0)+(1*4)=97
97 % 10 = 7
So 58200-04-7 is a valid CAS Registry Number.

58200-04-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name [3-[bis(2-chloroethyl)amino]-5-(carbamoylamino)phenyl]urea

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
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More Details:58200-04-7 SDS

58200-04-7Upstream product

58200-04-7Downstream Products

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