58202-67-8Relevant academic research and scientific papers
Direct difunctionalization of alkynes with sulfinic acids and molecular iodine: A simple and convenient approach to (E)-β-iodovinyl sulfones
Wei, Wei,Wen, Jiangwei,Yang, Daoshan,Jing, Huijun,You, Jinmao,Wang, Hua
, p. 4416 - 4419 (2015)
A simple and convenient approach for the construction of β-iodovinyl sulfones has been developed via direct difunctionalization of alkynes with sulfinic acids and molecular iodine. The present reaction provides a highly efficient approach to a diverse range of substituted (E)-β-iodovinyl sulfones in moderate to good yields with excellent stereo- and regio-selectivities but no need for any metal catalyst or additives.
Synthesis of (E)-iodo vinylsulfones via oxidative addition of thiol into alkyne under metal free condition
Samanta, Surya Kanta,Sarkar, Rumpa,Bera, Mrinal K.
, (2021/07/12)
An efficient, transition-metal free and molecular iodine promoted protocol for the construction of (E)-β-iodovinyl sulfone derivatives via oxidative C–S coupling of thiol and alkyne has been demonstrated. Both aryl and alkyl terminal acetylenes were found to be an excellent substrate for the present reaction which provides a wide range of β-iodovinyl sulfone derivatives with very good yield and excellent regio and stereo-selectivities. Diaryldisulfide is also found to be an equally efficient sulfonyl group surrogate under identical reaction conditions.
Stereoselective synthesis of difunctionalized 1,3-dienes containing tin and sulfonyl groups by palladium-catalyzed regio-and stereocontrolled addition reactions
Zhao, Hong,Yang, Weisen,Xie, Shiyun,Cai, Mingzhong
experimental part, p. 831 - 836 (2012/03/11)
Using palladium-catalyzed addition reactions, a terminal alkyne, an acetylenic sulfone, and a tin hydride comprise the building blocks for the construction of difunctionalized 1,3-dienes containing tin and sulfonyl groups in an atom-economical fashion. Te
Studies on hydrozirconation of 1-alkynyl sulfoxides or sulfones and the application for the synthesis of stereodefined vinyl sulfoxides or sulfones
Huang, Xian,Duan, Dehui,Zheng, Weixin
, p. 1958 - 1963 (2007/10/03)
The hydrozirconation reaction of 1-alkynyl sulfoxides or sulfones with CP2Zr(H)Cl in THF at room temperature predominantly gave Z-β-zirconated vinyl sulfoxides or sulfones with excellent regioselectivity. Compared with 1-alkynyl sulfoxides, the hydrozirconation reaction of 1-alkynyl sulfones exhibits great synthetic potential, leading to the efficient preparation of Z-β-halovinyl sulfones, Z-β-sulfonyl α,β-unsaturated ketones, and Z-β-alkynyl vinyl sulfones. Although the reaction mechanisms are still not clear, the neighboring group participation of the sulfinyl or sulfonyl group may be playing an important role in this unique hydrozirconation reaction.
