58211-57-7Relevant articles and documents
A chemobiological synthesis of eplerenone
Wuts, Peter G. M.,Anderson, Andrew M.,Ashford, Scott W.,Goble, Michael P.,White, Michael J.,Beck, Doris,Gilbert, Ivan,Hrab
, p. 418 - 422 (2008/09/17)
This paper will describe an approach to the synthesis of eplerenone, which is being marketed for the treatment of hypertension. The synthesis begins with DHEA available from wild yams and uses a combination of microbiological and chemical transformations to build eplerenone. Georg Thieme Verlag Stuttgart.
Processes for preparing C-7 substituted steroids
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Page/Page column 9, (2008/06/13)
This invention relates to processes for the preparation of novel 7-carboxy substituted steroid compounds of Formula I,
Microbial method for hydrolysis and oxidation of androst-5-ene and pregn-5-ene steroid esters
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, (2008/06/13)
A microbial method for hydrolysis and oxidation of androst-5-ene and pregn-5-ene steroid esters is disclosed.