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Dextrorphan, also known as dextrallorphan, is a psychoactive drug that serves as an active metabolite of the opioid medication dextromethorphan. Classified as a dissociative drug, it can induce hallucinations and a sense of detachment from reality. It operates by blocking NMDA receptors in the brain, which are integral to pain perception and memory function. Additionally, dextrorphan is a potent sigma-1 receptor agonist, potentially contributing to its psychoactive properties. It has been the subject of research for its potential in treating neurodegenerative diseases and as a supplement to opioid therapy, while also being misused recreationally for its hallucinogenic effects.

5822-43-5

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Basic information
1. Product Name: dextrallorphan
2. Synonyms: dextrallorphan;(9α,13α,14α)-17-(2-Propenyl)morphinan-3-ol
3. CAS NO:5822-43-5
4. Molecular Formula: C₁₉H₂₅NO
5. Molecular Weight: 283.41
6. EINECS: N/A
7. Product Categories: N/A
Chemical Properties
1. Melting Point: N/A
2. Boiling Point: 433.5°Cat760mmHg
3. Flash Point: 214.2°C
4. Appearance: /
5. Density: 1.14g/cm³
6. Vapor Pressure: 4.02E-08mmHg at 25°C
7. Refractive Index: 1.614
8. Storage Temp.: N/A
9. Solubility: N/A
10. CAS DataBase Reference: dextrallorphan(CAS DataBase Reference)
11. NIST Chemistry Reference: dextrallorphan(5822-43-5)
12. EPA Substance Registry System: dextrallorphan(5822-43-5)
Safety Data
1. Hazard Codes: N/A
2. Statements: N/A
3. Safety Statements: N/A
4. WGK Germany:
5. RTECS:
6. HazardClass: N/A
7. PackingGroup: N/A
8. Hazardous Substances Data: 5822-43-5(Hazardous Substances Data)

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5822-43-5 Usage

Uses

Used in Neurodegenerative Disease Treatment:
Dextrorphan is used as a therapeutic agent for neurodegenerative diseases, leveraging its ability to modulate NMDA receptors and potentially offering neuroprotective benefits.
Used in Opioid Therapy:
Dextrorphan is utilized as an adjunct to opioid therapy, where it may enhance the overall analgesic effect and potentially reduce the required dosage of opioids, thereby managing pain more effectively.
Used in Recreational Settings:
Although not recommended due to health risks and legal implications, dextrorphan is abused recreationally for its hallucinogenic properties, providing a sense of detachment and altered perception of reality.
Used in Research:
Dextrorphan is employed in scientific research as a tool to study the effects and mechanisms of NMDA receptor antagonism and sigma-1 receptor activation, furthering our understanding of their roles in various neurological conditions and potential therapeutic applications.

Check Digit Verification of cas no

The CAS Registry Mumber 5822-43-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,8,2 and 2 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 5822-43:
(6*5)+(5*8)+(4*2)+(3*2)+(2*4)+(1*3)=95
95 % 10 = 5
So 5822-43-5 is a valid CAS Registry Number.

InChI:InChI=1/C19H25NO/c1-2-10-20-11-9-19-8-4-3-5-16(19)18(20)12-14-6-7-15(21)13-17(14)19/h2,6-7,13,16,18,21H,1,3-5,8-12H2/t16-,18+,19-/m1/s1