582297-95-8Relevant academic research and scientific papers
Functionalized 4-aminoquinolines by rearrangement of pyrazole N-heterocyclic carbenes
Schmidt, Andreas,Muenster, Niels,Dreger, Andrij
supporting information; experimental part, p. 2790 - 2793 (2010/07/04)
(Figure Presented) Thermal decarboxylation of 1-phenyl pyrazolium-3- carboxylates from the mesomeric betaine class of substances leads to pyrazole-N-heterocyclic carbenes, which immediately rearrange to multiply substituted 4-aminoquinolines (see scheme). These species are of interest for the synthesis of heterocycles and pharmacologically active compounds.
