Cas 582306-95-4,5-Pyrimidinecarbonitrile, 4-amino-6-(2-methylphenyl)-2-phenyl-

582306-95-4

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Basic information

Product Name: 5-Pyrimidinecarbonitrile, 4-amino-6-(2-methylphenyl)-2-phenyl-
Synonyms:
CAS NO:582306-95-4
Molecular Formula: C18H14N4
Molecular Weight: 286.336
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: 5-Pyrimidinecarbonitrile, 4-amino-6-(2-methylphenyl)-2-phenyl-(CAS DataBase Reference)
NIST Chemistry Reference: 5-Pyrimidinecarbonitrile, 4-amino-6-(2-methylphenyl)-2-phenyl-(582306-95-4)
EPA Substance Registry System: 5-Pyrimidinecarbonitrile, 4-amino-6-(2-methylphenyl)-2-phenyl-(582306-95-4)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 582306-95-4(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 582306-95-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,8,2,3,0 and 6 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 582306-95:
(8*5)+(7*8)+(6*2)+(5*3)+(4*0)+(3*6)+(2*9)+(1*5)=164
164 % 10 = 4
So 582306-95-4 is a valid CAS Registry Number.

582306-95-4Upstream product

582306-95-4Downstream Products

582306-95-4Relevant academic research and scientific papers

One-step synthesis of aminopyrimidines from 5-oxo-4H-benzopyrans

Salfran, Esperanza,Suarez, Margarita,Verdecia, Yamila,Alvarez, Amaury,Ochoa, Estael,Martinez-Alvarez, Roberto,Seoaneb, Carlos,Martin, Nazario

, p. 509 - 516 (2004)

Novel 4-amino-6-aryl-2-phenylpyrimidine-5-carbonitriles have been prepared in one step procedure from the readily available 4-aryl-2-amino-3-cyano-5,6,7,8- tetrahydro-7,7-dimethyl-5-oxo-4H-benzopyrans. The mass spectroscopy study under EI conditions shows

Aminomethylpyrimidines as novel DPP-IV inhibitors: A 105-fold activity increase by optimization of aromatic substituents

Peters, Jens-Uwe,Weber, Silja,Kritter, Stephane,Weiss, Peter,Wallier, Angelina,Boehringer, Markus,Hennig, Michael,Kuhn, Bernd,Loeffler, Bernd-Michael

, p. 1491 - 1493 (2007/10/03)

The influence of aromatic substitution on a newly discovered class of inhibitors of dipeptidyl peptidase IV was investigated. A 105-fold increase in potency was achieved by the optimization of aromatic substituents in a parallel chemistry progr

Lead generation: Sowing the seeds for future success

Bleicher, Konrad H.,Nettekoven, Matthias,Peters, Jens-Uwe,Wyler, Rene

, p. 588 - 600 (2007/10/03)

Lead generation and the associated hit-to-lead process are key strategic elements in modern pharmaceutical research, and most companies have implemented this concept. Efficient lead generation is one of the main attempts to reduce the high attrition rates observed along the drug discovery process by focussing on the early developmental phases. The level of integration of the lead generation activities within the discovery organization, the flexibility in assessing and implementing new chemistries and new technologies, the high-quality standards set for the identification of the best possible chemical lead series will ultimately determine the future success in discovering new medicines.

Pyridine and pyrimidine derivatives

-

, (2008/06/13)

The present invention provides compounds of formula (I) wherein R1, R2, R3, R4 and X are as defined in the specification, and pharmaceutically acceptable salts thereof. The compounds are useful for the treatment

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