582311-67-9

Upstream product

• 18107-18-1 diazomethyl-trimethyl-silane 
• 118786-28-0 benzyl 2-methylene-4-phenylbutanoate 
• 16004-15-2 1-bromomethyl-4-iodobenzene 

Downstream Products

• 669776-05-0 2-{methoxy-[4-(2-trifluoromethyl-benzyl)-benzyl]-phosphinoylmethyl}-4-phenyl-butyric acid benzyl ester 
• 669776-01-6 2-{[4-(2-chloro-benzyl)-benzyl]-methoxy-phosphinoylmethyl}-4-phenyl-butyric acid benzyl ester 
• 669776-02-7 2-{[4-(2-ethyl-benzyl)-benzyl]-methoxy-phosphinoylmethyl}-4-phenyl-butyric acid benzyl ester 
• 669776-03-8 2-{[4-(2-ethoxy-benzyl)-benzyl]-methoxy-phosphinoylmethyl}-4-phenyl-butyric acid benzyl ester 
• 669775-69-3 2-{[4-(2-fluoro-benzyl)-benzyl]-methoxy-phosphinoylmethyl}-4-phenyl-butyric acid benzyl ester 
• 669775-95-5 2-{methoxy-[4-(2-methyl-benzyl)-benzyl]-phosphinoylmethyl}-4-phenyl-butyric acid benzyl ester 
• 669775-98-8 2-{methoxy-[4-(2-methoxy-benzyl)-benzyl]-phosphinoylmethyl}-4-phenyl-butyric acid benzyl ester 
• 669775-94-4 2-{[4-(4-fluoro-benzyl)-benzyl]-methoxy-phosphinoylmethyl}-4-phenyl-butyric acid benzyl ester 
• 669775-97-7 2-{methoxy-[4-(4-methyl-benzyl)-benzyl]-phosphinoylmethyl}-4-phenyl-butyric acid benzyl ester 
• 669776-00-5 2-{methoxy-[4-(4-methoxy-benzyl)-benzyl]-phosphinoylmethyl}-4-phenyl-butyric acid benzyl ester 
• 670226-95-6 [2-((S)-2,2-Dimethyl-1-methylcarbamoyl-propylcarbamoyl)-4-phenyl-butyl]-[4-(2-trifluoromethyl-benzyl)-benzyl]-phosphinic acid methyl ester 
• 670226-94-5 [2-((S)-2,2-Dimethyl-1-methylcarbamoyl-propylcarbamoyl)-4-phenyl-butyl]-[4-(2-ethoxy-benzyl)-benzyl]-phosphinic acid methyl ester 
• 670226-31-0 [2-((S)-2,2-Dimethyl-1-methylcarbamoyl-propylcarbamoyl)-4-phenyl-butyl]-[4-(2-methoxy-benzyl)-benzyl]-phosphinic acid methyl ester 
• 670226-90-1 [2-((S)-2,2-Dimethyl-1-methylcarbamoyl-propylcarbamoyl)-4-phenyl-butyl]-[4-(4-methoxy-benzyl)-benzyl]-phosphinic acid methyl ester 

Relevant academic research and scientific papers

Phosphinic acid-based MMP-13 inhibitors that spare MMP-1 and MMP-3

Phosphinic acid-based inhibitors of MMP-13 have been investigated with the aim of identifying potent inhibitors with high selectivity versus MMP-1. Independent variation of the substituents on a P1′ phenethyl group and a P2 benzyl gr