5825-43-4Relevant academic research and scientific papers
Iridium/Acid Cocatalyzed Direct Access to Fused Indoles via Transfer Hydrogenative Annulation of Quinolines and 1,2-Diketones
Jiang, Huanfeng,Lu, Guangpeng,Xie, Feng,Xie, Rong,Zhang, Min
, p. 2308 - 2312 (2020)
Herein, we present an unprecedented iridium/acid cocatalyzed construction of fused indoles via transfer hydrogenative annulation of nonactivated quinolines and 1,2-diketones. The products are assembled via initial reduction followed by selective coupling
Metal and Oxidant Free Construction of Substituted- and/or Polycyclic Indoles: A Useful Alternative to Bischler and Related Syntheses
De Crescentini, Lucia,Favi, Gianfranco,Mantellini, Fabio,Mari, Giacomo,Santeusanio, Stefania
supporting information, (2020/08/27)
A wide range of substituted indoles or polycyclic derivatives containing the indole core are easily accessible by acidic treatment of aromatic amines and 1,2-diaza-1,3-dienes. Unlike the related indole-Bischler synthesis, the regioselectivity of the method here reported is unique and predictable, the yields are generally good and also electron withdrawing substituted indoles are smoothly recovered.
Zirconium hydrazinediido complexes derived from cyclic hydrazines and their role in the catalytic synthesis of 1,7-annulated indoles
Scholl, Solveig A.,Wadepohl, Hubert,Gade, Lutz H.
supporting information, p. 937 - 940 (2013/03/28)
Reaction of cyclic 1,1′-disubstituted hydrazines with the bis(dimethylamido)zirconium complex [Zr{(NXyl)2N py} (NMe2)2] (1) in the presence of dmap yielded the hexacoordinate zirconium hydrazinediido
Addition Reactions of Heterocyclic Compounds. Part 77. Reaction of Dimethyl Acetylenedicarboxylate with 2- and 3-Alkyl Substituted Indoles and the Formation of (1+1 DMAD-CH4O) Adducts
Letcher, Roy M.,Choi, Michael C. K.,Acheson, R. Morrin,Prince, Richard J.
, p. 501 - 504 (2007/10/02)
Dimethyl acetylenedicarboxylate (DMAD) adds to 1,3-dimethylindole in moist acetic acid to give 2-substituted adducts.The dienone formulation for a product from 1,2,3-trimethylindole and DMAD has been confirmed by making use of proton-coupled 13C n.m.r. spectra.The generality of the formation of this (1+1 DMAD-CH4O) adduct is shown by the preparation of a further five new dienones including two bicyclopentadecadienones.
