58253-99-9

Usage

Uses

Used in Pharmaceutical Industry:
2,6-bis(tert-butylamino)-4-methylpyridin-3-yl methyl ketone is used as a building block for the synthesis of various drugs and active pharmaceutical ingredients. Its role in creating diverse chemical structures makes it a valuable component in drug development.
Used in Organic Synthesis:
2,6-bis(tert-butylamino)-4-methylpyridin-3-yl methyl ketone is used as a ligand in metal-catalyzed reactions, contributing to the formation of a wide array of chemical structures. Its versatility in organic synthesis is highly appreciated.
Used in Agrochemical Production:
2,6-bis(tert-butylamino)-4-methylpyridin-3-yl methyl ketone is used as an intermediate product in the synthesis of agrochemicals, playing a crucial role in the development of effective agricultural products.
Used in Fragrance and Dye Industries:
2,6-bis(tert-butylamino)-4-methylpyridin-3-yl methyl ketone is used in the synthesis of intermediate products for the production of fragrances and dyes, enhancing the variety and quality of these products.

InChI:InChI=1/C16H27N3O/c1-10-9-12(18-15(3,4)5)17-14(13(10)11(2)20)19-16(6,7)8/h9H,1-8H3,(H2,17,18,19)

Upstream product

• 10513-45-8 2-tert-butyl-5-methylisoxazolium perchlorate 

Relevant academic research and scientific papers

4-Alkyl-2,6-di(secondary or tertiary alkylamino) pyridines, compositions thereof and methods for treating diabetes and obesity

Compounds of the formula STR1 wherein R is secondary alkyl of 3 to 7 carbon atoms or tertiary alkyl of 4 to 7 carbon atoms, R' is secondary alkyl of 3 to 7 carbon atoms or tertiary alkyl of 4 to 7 carbon atoms, R1 is alkyl of 1 to 4 carbon atoms, R2 is hydrogen, chloro or bromo, and R3 is hydrogen, --CO--R4 or cyano, Wherein R4 is alkyl of 1 to 4 carbon atoms, alkoxy of 1 to 3 carbon atoms, STR2 OR AMINO, WHEREIN EACH X is independently alkyl of 1 to 3 carbon atoms, alkoxy of 1 to 3 carbon atoms or halo or two X's on adjacent carbon atoms together are methylenedioxy, with the proviso that the ortho positions of the phenyl ring are free of halo substituents, and n is 0, 1, 2 or 3, And the pharmaceutically acceptable acid addition salts thereof, Are useful as anti-obesity and anti-diabetic agents. The compounds wherein R2 is hydrogen and R3 is alkylcarbonyl, benzoyl or substituted benzoyl are synthesized from ketoketenimines and amidines while those wherein R2 is hydrogen and R3 is alkylcarbonyl are also synthesized from isoxazolium salts and ammonia. The compounds wherein R2 is hydrogen and R3 is cyano are synthesized from the corresponding 2,6-dihalopyridines as are many of the other compounds. The compounds wherein R2 is hydrogen and R3 is alkylcarbonyl, alkoxycarbonyl or carbamoyl are synthesized from the corresponding cyano compounds. The compounds wherein R2 is hydrogen and R3 is (C2-4 alkyl) carbonyl are also synthesized from the corresponding compounds wherein R3 is acetyl. The compounds wherein R2 is chloro or bromo are synthesized from the corresponding compounds wherein R2 is hydrogen and an N-halosuccinimide. The compounds wherein R3 is hydrogen are synthesized from the corresponding alkylcarbonyl compounds or 2,6-dihalopyridines.