58294-24-9Relevant articles and documents
Studies on ring opening reactions of N-phenylsulfonyl substituted spiro-β-lactams
Croce, Piero Dalla,La Rosa, Concetta
, p. 2653 - 2660 (2007/10/03)
Ring opening reactions of the spiro-β-lactam 5-benzoyl-3-phenyl-2-phenylsulfonyl-7-thia-2,5-diazaspiro[3.4]octan-1-one (1a) under hydrolytic, reductive and alkylating reaction conditions are reported. There is evidence for the influence of the spiro struc
Synthesis of imidazoles via hetero-cope rearrangements
Lantos,Zhang,Shui,Eggleston
, p. 7092 - 7095 (2007/10/02)
A novel synthetic approach to heterocycles containing the imidazole moiety based on the multihetero-Cope rearrangement is described. Oximes are reacted with benzenecarboximidoyl chlorides 4 affording adducts that readily undergo the hetero-Cope rearrangement at slightly elevated temperatures. Acid treatment of the resulting amidines 8 provides imidazoles in very high yields.