58294-24-9Relevant academic research and scientific papers
Studies on ring opening reactions of N-phenylsulfonyl substituted spiro-β-lactams
Croce, Piero Dalla,La Rosa, Concetta
, p. 2653 - 2660 (2007/10/03)
Ring opening reactions of the spiro-β-lactam 5-benzoyl-3-phenyl-2-phenylsulfonyl-7-thia-2,5-diazaspiro[3.4]octan-1-one (1a) under hydrolytic, reductive and alkylating reaction conditions are reported. There is evidence for the influence of the spiro struc
INTERMOLECULAR INTERACTIONS THAT DETERMINE THE REGIOSELECTIVITY IN 1,3-DIPOLAR CYCLOADDITIONS OF N-METHYL-1,3-OXAZOLIUM-5-OLATES WITH N-(PHENYLMETHYLENE)BENZENESULPHONAMIDE
Bonati, L.,Ferraccioli, R.,Moro, G.
, p. 452 - 462 (2007/10/02)
1,3-Dipolar cycloadditions of N-(phenylmethylene)benzenesulphonamide with mesoionic N-methyl-1,3-oxazolium-5-olates give 2,5-disubstituted imidazole derivatives with high regioselectivity.The intermolecular interactions underlying this regioselectivity we
Synthesis of imidazoles via hetero-cope rearrangements
Lantos,Zhang,Shui,Eggleston
, p. 7092 - 7095 (2007/10/02)
A novel synthetic approach to heterocycles containing the imidazole moiety based on the multihetero-Cope rearrangement is described. Oximes are reacted with benzenecarboximidoyl chlorides 4 affording adducts that readily undergo the hetero-Cope rearrangement at slightly elevated temperatures. Acid treatment of the resulting amidines 8 provides imidazoles in very high yields.
