583031-18-9Relevant academic research and scientific papers
3,4-Dihydro-2H-benzoxazinones are 5-HT1A receptor antagonists with potent 5-HT reuptake inhibitory activity
Atkinson, Peter J.,Bromidge, Steven M.,Duxon, Mark S.,Gaster, Laramie M.,Hadley, Michael S.,Hammond, Beverley,Johnson, Christopher N.,Middlemiss, Derek N.,North, Stephanie E.,Price, Gary W.,Rami, Harshad K.,Riley, Graham J.,Scott, Claire M.,Shaw, Tracey E.,Starr, Kathryn R.,Stemp, Geoffrey,Thewlis, Kevin M.,Thomas, David R.,Thompson, Mervyn,Vong, Antonio K.K.,Watson, Jeannette M.
, p. 737 - 741 (2007/10/03)
Starting from a high throughput screening hit, a series of 3,4-dihydro-2H-benzoxazinones has been identified with both high affinity for the 5-HT1A receptor and potent 5-HT reuptake inhibitory activity. The 5-(2-methyl)quinolinyloxy derivative
BENZOXAZINONE DERIVATIVES, PREPARATION THEREOF AND USES IN THE TREATMENT OF CNS AND OTHER DISORDERS
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Page 36, (2008/06/13)
Compounds of formula (I) and pharmaceutically acceptable salts thereof are disclosed:wherein A, R1, R2, R3, p, q, A and X are as defined in the specification. Preparation of the compounds and uses in the treatment of CNS and other disorders, including dep
