58314-12-8Relevant articles and documents
Promoting helicity in carbohydrate-containing foldamers through long-range hydrogen bonds
Rodriguez-Lucena, David,Benito, Juan M.,Mellet, Carmen Ortiz,Garcia Fernandez, Jose M.
, p. 831 - 833 (2007)
A sensor system to probe the propensity of carbohydrates to induce helical structures through long-range hydrogen bonds, based on a C2-symmetric xylylene bis(thiourea) arrangement, is reported; the formation of intermolecular complexes with ben
Novel sugar ureide and thioureide derivatives
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, (2008/06/13)
Novel sugar ureide and thioureide derivatives are provided by this invention, which exhibit certain antibacterial activity against a variety of gram-positive and gram-negative bacteria and useful in therapeutic treatment of bacterial infections. The compounds have the formula STR1 wherein R1 is a monovalent residue of aldose, aldonic acid and their 2-amino derivatives, R2 is an aralkyl, heterocyclic, sulfamoylaryl, R3 CONH or R4 NH-- where R3 is a heterocyclic and R4 is an aryl group and Y is oxygen or sulfur atom, which are prepared by reacting an isocyanate or isothiocyanate of the formula R1 NC=Y with an amino compound of the formula R2 NH2.