58371-83-8

Upstream product

• 55176-26-6 2-Phenyl-4-(3,4-dimethoxyphenyl)-5,6-tetramethylene-6H-thiopyran 
• 54146-67-7 2-[1-(3,4-Dimethoxy-phenyl)-3-oxo-3-phenyl-propyl]-cyclohexanone 
• 106240-82-8 4-(3,4-Dimethoxy-phenyl)-2-phenyl-5,6,7,8-tetrahydro-4H-thiochromene 
• 54146-67-7 1-phenyl-3-(3,4-dimethoxyphenyl)-3-(2-oxocyclohexyl)-1-propanone 
• 76-05-1 trifluoroacetic acid 
• 94594-89-5 3-Phenyl-5-(3,4-dimethoxyphenyl)-2-thiabicyclo<4,4,0>decane-Δ^1,6 

Relevant academic research and scientific papers

UN UNUSUAL PRODUCT OF THE REACTION OF l-PHENYL-3-(3,4-DIMETHOXYPHENYL)-3-(2-OXOCYCLOHEXYL)-1-PROPANONE WITH HYDROGEN SULFIDE AND ACIDS: 2α-PHENYL-2,4-ortho-(14,15-DIMETHOXYBENZO)-cis-1-THIADECALIN

The reaction of 1-phenyl-3-(3,4-dimethoxyphenyl)-3-(2-oxocyclohexyl)-1-propanone with hydrogen sulfide and acids gives an intramolecular rearrangement product, 2α-phenyl-2,4-ortho-(14,15-dimethoxybenzo)-cis-1-thiadecalin in addition to the unusual products of disproportionation of intermediate 2-phenyl-4-(3,4-dimethoxyphenyl)-5,6-tetramethylene-4H-thiopyran, namely, 5,6-tetramethylenethiopyrilium salts and 2α-phenyl-4α-(3,4-dimethoxyphenyl)-cis-1-thiadecalin.The configurational and conformational assignments for the sulfides, their sulfoxides, and sulfones were made by 13C NMR spectroscopy.

CONFIGURATIONALLY AND CONFORMATIONALLY HOMOGENEOUS ARYL-cis-1-THIADECALINS

The structure of aryl-substituted cis-1-thiadecalins formed together with 5,6-tetramethylenethiopyrylium salts in disproportionation reactions of condensed 4H-, 6H-thiopyrans and dihydrothiopyrans with CF3COOH, as well as in the ionic reduction of the latter by the ion pair trifluoroacetic acid-triethylsilane, was studied.It was shown that the reduction proceeds stereospecifically with the formation of configurationally and conformationally homogeneous aryl-cis-1-thiadecalins possessing 2α-R1- and 2α-R1-4α-R2-configurations.The configurational and conformational assignments were made by the 13C NMR method.

REACTIONS OF "SEMICYCLIC" 1,5-DIKETONES WITH HYDROGEN SULFIDE AND TRIFLUOROACETIC ACID

The reactions of known and new "semicyclic" 1,5-diketones with hydrogen sulfide and with trifluoroacetic acid were studied.It was shown that under the investigated conditions both 1-aryl- and 1,3-diaryl-substituted diketones form 3R-5R-2-thiabicycloalkane