58407-22-0Relevant academic research and scientific papers
Organoselenium-based synthesis of oxygen-containing prostacyclins
Nicolaou,Barnette,Magolda
, p. 3480 - 3485 (2007/10/02)
The application of organoselenium-induced ring closures to the synthesis of stable, oxygen-containing prostacyclins is described. The strategy involves utilization of PGF2α methyl ester (3) as a starting material in a PhSeCl-induced cyclization
8β,12α,15β-PGF2 β Compounds
-
, (2008/06/13)
This invention is a group of 8-beta, 12-alpha-PG2 (prostaglandin-type) analogs having variable chain length, or methyl or phenyl substitution in the hydroxy-substituted side-chain, and processes for making them. These compounds are useful for a variety of pharmacological purposes, including anti-ulcer, inhibition of platelet aggregation, increase of nasal patency, and labor inducement at term.
