58408-93-8Relevant academic research and scientific papers
Efficient synthesis of 2-arylamino substituted pyridinyl nitriles by Buchwald-Hartwig amination
Guo, Shuo,Wang, Yaping,Sun, Chunxia,Li, Jingya,Zou, Dapeng,Wu, Yangjie,Wu, Yusheng
supporting information, p. 3233 - 3237 (2013/06/27)
Both nitrile and arylamino groups containing pyridine derivatives are synthesized from commercially available nitrile substituted pyridyl chlorides via a palladium-BINAP catalyst (the second generation catalyst for the amination) in moderate to good yields. The mild conditions permit the presence of base sensitive functional groups. Noteably, the halogen atoms linked to the aromatic ring were maintained in the structures of the products under the amination reaction conditions.
Photochemically Induced Electron Transfer from Aniline Derivatives to Pyridine-2,4-dicarbonitrile: Synthetic and Mechanistic Aspects
Bernardi, Rosanna,Caronna, Tullio,Morrocchi, Sergio,Vittimberga, Bruno M.
, p. 1411 - 1415 (2007/10/02)
A study on the photochemically induced electron transfer from substituted aniline donors to a 2,4-dicyanopyridine acceptor permits the synthesis of new amino derivatives of the pyridine and forms the basis of a hypothesis on the mechanism of the reaction and the influence of the substituent on the aniline ring.
