58414-75-8Relevant academic research and scientific papers
Ni-Catalyzed Divergent Cyclization/Carboxylation of Unactivated Primary and Secondary Alkyl Halides with CO2
Wang, Xueqiang,Liu, Yu,Martin, Ruben
, p. 6476 - 6479 (2015)
A user-friendly Ni-catalyzed reductive cyclization/carboxylation of unactivated alkyl halides with CO2 is described. The protocol operates under mild conditions with an excellent chemoselectivity profile and a divergent syn/anti selectivity pat
Substituted thienyl-acetic acid esters
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, (2008/06/13)
Substituted thienyl-acetic acid esters of the formula: STR1 in which R1 and R2 each, independently is H, CH3, C2 H5, C3 H7, OCH3, SCH3, Cl Br or NO2, R3 is phenyl or cyclohexyl and R4 is H, or R3 and R4 together are cyclohexylidene, n is 2 or 3, and A is monoalkylamino or dialkylamino, each alkyl radical having 1 to 4 carbon atoms, or amino derived from a cycloalkylamine of 5 to 7 chain members which may contain an additional hetero-atom, provided that each of R1 and R2 is not H if R3 is phenyl or cyclohexyl and R4 is H, racemates, optical isomers, and their pharmaceutically acceptable acid addition salts and quaternary ammonium salts obtained with alkyl halides, have marked activity as peripheral vasodilators, platelet aggregation inhibitors, spasmolytic agents, coronary and cerebral vasodilators, and papaverine-like activity.
