58426-99-6Relevant articles and documents
Synthetic Utility of Arylmethylsulfones: Annulative π-Extension of Aromatics and Hetero-aromatics Involving Pd(0)-Catalyzed Heck Coupling Reactions
Sankar, Elumalai,Raju, Potharaju,Karunakaran, Jayachandran,Mohanakrishnan, Arasambattu K.
, p. 13583 - 13593 (2017/12/26)
A straightforward and general method for the synthesis of annulated thiophene, dibenzothiophene, and carbazoles analogues has been achieved involving alkylation of 2-bromo-1-(phenylsulfonylmethyl)arene/heteroarene with arylmethyl bromides/heteroarylmethyl bromides using t-BuOK as a base in DMF, followed by Pd(0)-mediated intramolecular Heck coupling in the presence of K2CO3 in DMF at 80-140 °C. The attractive feature of this protocol is that a wide variety of π-conjugated heterocycles could be readily accessed by an appropriate choice of arylmethylsulfones and benzylic bromides.
Studies of Polycyclic Thiaarenes: Part II. An Improved Synthesis of Phenanthrothiophene and a Synthesis of Acenaphthonaphthothiophene, a Novel Polynuclear Thiaarene
Kar, Gandhi K.,Karmakar, Arun C.,Ray, Jayanta K.
, p. 999 - 1002 (2007/10/02)
An improved synthesis of phenanthrothiophene (6) from 1-chloro-3,4-dihydrophenanthrene-2-aldehyde (2) by condensation with thioglycolate followed by hydrolysis, decarboxylation and dehydrogenation is described.A new polycyclic thiophene derivative 14 has also been prepared from acenaphthothiophene (7) by Friedel-Craft's reaction with phthalic anhydride followed by lactonization of the keto carboxylic acid 9 and then reduction and finally cyclisation of the resultant aldehyde 13.
