58458-10-9 Usage
Uses
Used in Organic Synthesis:
2-bromo-3-(trifluoromethyl)aniline is used as a versatile reagent in organic synthesis for its ability to participate in various chemical reactions, including cross-coupling and nucleophilic substitution. Its presence of bromine and trifluoromethyl groups allows for the formation of complex organic compounds.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 2-bromo-3-(trifluoromethyl)aniline is used as a valuable intermediate for the development of new drugs. Its unique structure and functional groups contribute to the creation of potential drug candidates with novel therapeutic properties.
Used in Academic Research:
2-bromo-3-(trifluoromethyl)aniline is utilized in academic research for the study of organic reactions and mechanisms. Its reactivity and structural features provide insights into the understanding of chemical processes and the development of new synthetic methodologies.
It is important to handle 2-bromo-3-(trifluoromethyl)aniline with care, as both bromine and trifluoromethyl groups are known to be toxic and potentially hazardous to human health and the environment.
Check Digit Verification of cas no
The CAS Registry Mumber 58458-10-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,8,4,5 and 8 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 58458-10:
(7*5)+(6*8)+(5*4)+(4*5)+(3*8)+(2*1)+(1*0)=149
149 % 10 = 9
So 58458-10-9 is a valid CAS Registry Number.
InChI:InChI=1/C7H5BrF3N/c8-6-4(7(9,10)11)2-1-3-5(6)12/h1-3H,12H2
58458-10-9Relevant academic research and scientific papers
Electrophilic bromination of meta-substituted anilines with N-bromosuccinimide: Regioselectivity and solvent effect
Bartoli, Sandra,Cipollone, Amalia,Squarcia, Antonella,Madami, Andrea,Fattori, Daniela
experimental part, p. 1305 - 1308 (2009/12/24)
N-Bromosuccinimide-mediated electrophilic aromatic bromination of a series of anilines substituted with an electron-with-drawing group in the meta position was investigated. The regioselectivity of the reaction is markedly dependent on the polarity of the solvent and the bromination reaction can be tuned by appropriate selection of the reaction medium. Georg Thieme Verlag Stuttgart.
