58458-10-9 Usage
General Description
2-bromo-3-(trifluoromethyl)aniline is a chemical compound that is commonly used in organic synthesis and pharmaceutical research. It is a derivative of aniline, a common building block in the production of dyes, pigments, and pharmaceuticals. The presence of the bromine and trifluoromethyl groups in the compound makes it a versatile reagent for various chemical reactions, including cross-coupling and nucleophilic substitution. Its unique structure and functional groups make it a valuable intermediate for the synthesis of complex organic compounds. This chemical has potential applications in the pharmaceutical industry for the development of new drugs and in academic research for the study of organic reactions and mechanisms. Additionally, it is important to handle this compound with care, as both bromine and trifluoromethyl groups are known to be toxic and potentially hazardous to human health and the environment.
Check Digit Verification of cas no
The CAS Registry Mumber 58458-10-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,8,4,5 and 8 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 58458-10:
(7*5)+(6*8)+(5*4)+(4*5)+(3*8)+(2*1)+(1*0)=149
149 % 10 = 9
So 58458-10-9 is a valid CAS Registry Number.
InChI:InChI=1/C7H5BrF3N/c8-6-4(7(9,10)11)2-1-3-5(6)12/h1-3H,12H2
58458-10-9Relevant articles and documents
Electrophilic bromination of meta-substituted anilines with N-bromosuccinimide: Regioselectivity and solvent effect
Bartoli, Sandra,Cipollone, Amalia,Squarcia, Antonella,Madami, Andrea,Fattori, Daniela
experimental part, p. 1305 - 1308 (2009/12/24)
N-Bromosuccinimide-mediated electrophilic aromatic bromination of a series of anilines substituted with an electron-with-drawing group in the meta position was investigated. The regioselectivity of the reaction is markedly dependent on the polarity of the solvent and the bromination reaction can be tuned by appropriate selection of the reaction medium. Georg Thieme Verlag Stuttgart.
