5847-73-4

Basic information

• Product Name: 2-[(E)-2-(3-methoxyphenyl)ethenyl]pyridine
• CAS NO: 5847-73-4
• Molecular Formula: C₁₄H₁₃NO
• Molecular Weight: 211.2591
• Mol File: 5847-73-4.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 344.2°C at 760 mmHg
• Flash Point: 125.8°C
• Density: 1.112g/cm³
• Vapor Pressure: 0.000133mmHg at 25°C
• Refractive Index: 1.64
• CAS DataBase Reference: 2-[(E)-2-(3-methoxyphenyl)ethenyl]pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[(E)-2-(3-methoxyphenyl)ethenyl]pyridine(5847-73-4)
• EPA Substance Registry System: 2-[(E)-2-(3-methoxyphenyl)ethenyl]pyridine(5847-73-4)

Safety Data

• Hazardous Substances Data: 5847-73-4(Hazardous Substances Data)

Upstream product

• 626-55-1 3-Bromopyridine 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 78-08-0 Triethoxyvinylsilane 
• 3319-15-1 rac-1-(4-methoxyphenyl)-ethanol 
• 637-69-4 4-Methoxystyrene 
• 99-96-7 4-hydroxy-benzoic acid 
• 105-13-5 4-Methoxybenzyl alcohol 
• 824-94-2 p-methoxybenzyl chloride 
• 121-98-2 methyl 4-methoxybenzoate 
• 2746-25-0 p-Methoxybenzyl bromide 
• 1121-55-7 3-vinylpyridine 
• 1121-60-4 pyridine-2-carbaldehyde 
• 1145-93-3 diethyl 4-methoxybenzylphosphonate 
• 500-22-1 3-pyridinecarboxaldehyde 

Downstream Products

• 879009-51-5 ethyl [4-[(E)-2-pyridin-3-ylvinyl]phenoxy]acetate 
• 85666-05-3 4-[(E)-2-(pyridin-3-yl)ethenyl]phenol 

Relevant articles and documents

A new insight into the push-pull effect of substituents via the stilbene-like model compounds

In this paper, authors report on 1-pyridyl-2-arylethenes, 1-furyl-2-arylethylenes, 1,2-diphenylpropylenes and substituted cinnamyl anilines as stilbene-like model compounds to investigate the factors dominating the push-pull effect of substituents via usi

THERAPEUTIC AGENTS FOR SKIN DISEASES AND CONDITIONS

The present invention relates to method(s) of treating a subject afflicted with a skin disease or condition, the method comprising administering to the subject or patient in need a composition comprising a therapeutically effective amount of a substituted cis or trans- stilbene or a stilbene hybrid. A method of treating or reducing the likelihood of a skin disease or condition in a patient is an additional embodiment of the present invention. Preferred pharmaceutical compositions of the invention include nanoemulsions comprising a therapeutically effective amount of a substituted cis or trans-stilbene or stilbene hybrid and at least one antibiotic.

Mechanistic studies on the Pd-catalyzed vinylation of aryl halides with vinylalkoxysilanes in water: The effect of the solvent and NaOH promoter

The mechanism of the Pd-catalyzed vinylation of aryl halides with vinylalkoxysilanes in water has been studied using different catalytic precursors. The NaOH promoter converts the initial vinylalkoxysilane into a highly reactive water-soluble vinylsilanolate species. Similarly, deuterium-labeling experiments have shown that, irrespective of the catalytic precursor used, vinylation occurs exclusively at the CH vinylic functionality via a Heck reaction and not at the C-Si bond via a Hiyama cross-coupling. The involvement of a Heck mechanism is interpreted in terms of the reduced nucleophilicity of the base in water, which disfavors the transmetalation step. The Heck product (β-silylvinylarene) undergoes partial desilylation, with formation of a vinylarene, by three different routes: (a) hydrolytic desilylation by the aqueous solvent (only at high temperature); (b) transmetalation of the silyl olefin on the PdH Heck intermediate followed by reductive elimination of vinylarene; (c) reinsertion of the silyl olefin into the PdH bond of the Heck intermediate followed by β-Si syn-elimination. Both the Hiyama and Heck catalytic cycles and desilylation mechanisms b and c have been computationally evaluated for the [Pd(en)Cl2] precursor in water as solvent. The calculated Gibbs energy barriers support the reinsertion route proposed on the basis of the experimental results.