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Usage

Uses

Used in Organic Synthesis:
1-(3-aminopropoxy)naphthalene is used as a building block in organic synthesis for the creation of more complex molecules, contributing to the development of various chemical products.
Used in Pharmaceutical Production:
In the pharmaceutical industry, 1-(3-aminopropoxy)naphthalene is utilized as a key component in the production of drugs, leveraging its unique chemical properties to enhance medicinal formulations.
Used in Dye Manufacturing:
1-(3-aMinopropoxy)naphthalene also finds application in the dye industry, where it serves as a crucial ingredient in the synthesis of various dyes, adding to their color spectrum and performance characteristics.
Used in Research:
1-(3-aminopropoxy)naphthalene is employed as a research chemical, enabling scientists to explore its properties and potential applications in advancing chemical and material sciences.

Upstream product

• 90-15-3 α-naphthol 
• 102196-49-6 2-[3-(naphthalen-1-yloxy)propyl]-1H-isoindole-1,3(2H)-dione 

Relevant academic research and scientific papers

N-(Phthalimidoalkyl) Derivatives of Serotonergic Agents: A Common Interaction at 5-HT1A Serotonin Binding Sites ?

Several classes of agents are known to bind at central 5-HT1a serotonin sites.In order to challenge the hypothesis that these agents bind in a relatively similar manner (i.e., share common aryl and terminal amine sites), we prepared N-(phthalimidobutyl) derivatives of examples of several such agents.With regard to arylpiperazines, we had previously shown that introduction of this functionality at the terminal amine is tolerated by the receptor and normally results in a significant (>10-fold) enhancement in affinity.The results of the present study show that this bulky functionality is also tolerated by the receptor when incorporated into examples of all other major classes of 5-HT1A agents (e.g., 2-aminotetralin, phenylalkylamine, indolylalkylamine, and (aryloxy)alkylamine derivatives).The length of the alkyl chain that separates the terminal amine from the phthalimido group is of major importance, and a four-carbon chain appears optimal.Alteration of the length of this chain can have a significant influence on affinity; decreasing the chain length from four to three carbon atoms can reduce affinity by an order of magnitude, and further shortening can have an even more pronounced effect.