58480-17-4

Basic information

• Product Name: 2,3-DIMETHYLNAPHTHO[1,2-D]THIAZOLIUM TOSYLATE
• Synonyms: AURORA KA-87;2,3-DIMETHYLNAPHTHO[1,2-D]THIAZOLIUM TOSYLATE;SALOR-INT L203238-1EA;2-d]thiazolium,1,2-dimethyl-naphtho[saltwith4-methylbenzenesulfonicacid;1,2-dimethylnaphtho[1,2-d]thiazolium toluene-p-sulphonate;1,2-Dimethyl-beta-naphthothiazolium p-tosylate;Einecs 261-283-6;Naphtho(1,2-D)thiazolium, 1,2-dimethyl-, 4-methylbenzenesulfonate (1:1)
• CAS NO: 58480-17-4
• Molecular Formula: C₇H₇O₃S*C₁₃H₁₂NS
• Molecular Weight: 385.5
• EINECS: 261-283-6
• Mol File: 58480-17-4.mol
• Article Data: 2

Chemical Properties

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: g/cm³
• CAS DataBase Reference: 2,3-DIMETHYLNAPHTHO[1,2-D]THIAZOLIUM TOSYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-DIMETHYLNAPHTHO[1,2-D]THIAZOLIUM TOSYLATE(58480-17-4)
• EPA Substance Registry System: 2,3-DIMETHYLNAPHTHO[1,2-D]THIAZOLIUM TOSYLATE(58480-17-4)

Safety Data

• Hazardous Substances Data: 58480-17-4(Hazardous Substances Data)

Usage

Type of compound

Thiazolium salt

Common uses

Organic synthesis catalyst, strong alkylating agent, potential medicinal treatment, preparation of dyes and other organic compounds

Known for

Ability to transfer alkyl groups to various nucleophiles

InChI:InChI=1/C13H12NS/c1-9-14(2)13-11-6-4-3-5-10(11)7-8-12(13)15-9/h3-8H,1-2H3/q+1

Upstream product

• 80-48-8 methyl p-toluene sulfonate 
• 2682-45-3 2-methylnaphtho[1,2-d]thiazole 

Downstream Products

• 2950-58-5 3-methyl-2-[2-(N-methyl-2-methylsulfanyl-anilino)-2-phenyl-vinyl]-benzothiazolium; iodide 
• 2785-01-5 1,3-bis-(1-methyl-naphtho[1,2-d]thiazol-2-yl)-trimethinium; iodide 
• 1042-84-8 2-(1-methyl-1H-naphtho[1,2-d]thiazol-2-ylidene)-1-phenyl-ethanone 
• 2783-65-5 1-methyl-2-(3-methyl-2-phenyl-2,3-dihydro-benzothiazol-2-ylmethylene)-1,2-dihydro-naphtho[1,2-d]thiazole 
• 73075-42-0 2-ethyl-1,3-bis-(1-methyl-naphtho[1,2-d]thiazol-2-yl)-trimethinium ; bromide 
• 18244-77-4 1,3-bis-(1-methyl-naphtho[1,2-d]thiazol-2-yl)-2-phenyl trimethinium ; bromide 
• 2862-22-8 3,3'-dimethyl-2-phenyl-2,3,2',3'-tetrahydro-2,2'-methanylylidene-bis-benzothiazole 
• 62609-97-6 1-methyl-2-[2-(2-methyl-indol-3-yl)-propenyl]-naphtho[1,2-d]thiazolium; toluene-4-sulfonate 

Relevant articles and documents

New hexamethine indothia-cyanines: Synthesis and photophysical properties as well as both antitumor activity and imaging

Six new hexamethine indothia-cyanines were successfully synthesized by integrating a benzothiazole or naphthothiazole and indole unit using isophorone. These cyanines exhibited strong absorption and near-infrared fluorescence with a large stokes shift, and showed excellent stability. And they were tested as novel anticancer agents in vitro against human breast cancer cells (MCF-7), and indothia-cyanine D1 could efficiently reduce MCF-7 viability and exhibited no toxicity against normal human immortalized epidermal cells (Hacat). Cyanine D1 was further studied for its antitumor activity in mice. The in vivo result indicated that D1 could significantly inhibit the growth of breast tumors from tumor-bearing mice, and had no effect on the normal functions of the vital organs in vivo. In addition, D1 could stain MCF-7 cells and emitted bright red fluorescence, being a potential functional agent with both imaging and antitumor activity.