58534-46-6 Usage
General Description
(Z)-Desmethyldoxepin, also known as desmethyldoxepin, is a chemical compound that is an active metabolite of the tricyclic antidepressant doxepin. It is a selective antagonist of the histamine H1 receptor and possesses significant sedative effects. It is also used as an antipruritic agent for the treatment of conditions such as pruritus, urticaria, and atopic dermatitis. The chemical has been found to be effective in reducing itching and promoting sleep, and its sedative properties make it a potential treatment for insomnia. Additionally, (Z)-Desmethyldoxepin has been studied for its potential role in the management of anxiety-related disorders. Overall, (Z)-Desmethyldoxepin is a pharmacologically active compound with therapeutic potential in the treatment of various conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 58534-46-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,8,5,3 and 4 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 58534-46:
(7*5)+(6*8)+(5*5)+(4*3)+(3*4)+(2*4)+(1*6)=146
146 % 10 = 6
So 58534-46-6 is a valid CAS Registry Number.
58534-46-6Relevant articles and documents
N-DESMETHYL-DOXEPIN AND METHODS OF USING THE SAME TO TREAT SLEEP DISORDERS
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, (2010/11/29)
The invention relates to desmethyldoxepin, isomers of desmethyldoxepin, and pharmaceutically acceptable salts and prodrugs of desmethyldoxepin; compositions containing the same, and the use of any of the aforementioned for the treatment of sleep disorders.
EFFICIENT SYNTHESIS OF TRICYCLIC ANTIDEPRESSANT NORMETABOLITES
Adamczyk, Maciek,Fishpaugh, Jeffrey R.,Johnson, Donald
, p. 168 - 171 (2007/10/03)
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