58544-49-3

Upstream product

• 917-54-4 methyllithium 
• 21139-18-4 4,6-dimethyl-1-phenyl-2-oxopyrimidine 
• 917-64-6 methyl magnesium iodide 

Downstream Products

• 80935-70-2 2-anilino-2-methylpentan-4-one oxime 
• 81730-00-9 3,4,5,6-tetrahydro-4,6,6-trimethyl-1-phenyl-2-(1H)pyrimidinone 
• 81729-98-8 2,N⁴-Dimethyl-N²-phenyl-pentane-2,4-diamine 

Relevant academic research and scientific papers

Reaction of Pyrimidin-2(1H)-ones and -thiones with Organometallic Compounds. Regioselective Preparation of Dihydropyrimidin-2(1H)-ones and -thiones

4,6-Dimethyl-1-phenylpyrimidin-2(1H)-one (1) reacted with methylmagnesium iodide to afford 4,6,6-trimethyl-1-phenyl-3,6-dihydropyrimidin-2(1H)-one (8a) selectively; compound (1) reacted with methyl-lithium to give mainly 4,4,6-trimethyl-1-phenyl-3,4-dihydropyrimidin-2(1H)-one (8b).The reactions of various pyrimidin-2(1H)-ones and -thiones with organometallic compounds, and the influence of bulkiness of alkyl groups upon the product ratio, are also discussed.