58544-87-9

Upstream product

• 552-41-0 1-(2-hydroxy-4-methoxyphenyl)ethanone 
• 6346-05-0 3-benzyloxy-4-methoxybenzaldehyde 
• 89-84-9 2',4'-dihydroxy-4-acetophenone 

Downstream Products

• 90902-21-9 1-(2'-hydroxy-4'-methoxyphenyl)-3-(3-hydroxy-4-methoxyphenyl)-propane 
• 58544-88-0 2-(3-benzyloxy-4-methoxy-phenyl)-3-hydroxy-7-methoxy-chromen-4-one 
• 93876-56-3 2-(3-hydroxy-4-methoxyphenyl)-3,7-dimethoxy-4H-chromen-4-one 
• 2552-72-9 3-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-7-methoxy-4H-chromen-4-one 
• 97257-15-3 3'-benzyloxy-3,7,4'-trimethoxyflavone 

Relevant academic research and scientific papers

3′-Hydroxy-3,4′-dimethoxyflavone blocks tubulin polymerization and is a potent apoptotic inducer in human SK-MEL-1 melanoma cells

Flavonoids are naturally occurring polyphenolic compounds and are among the most promising anticancer agents. A series of flavonols and their 3-methyl ether derivatives were synthesized and assessed for cytotoxicity. It was found that 3′-hydroxy-3,4′-dime

SYNTHESIS OF THREE NATURAL 1,3-DIARYLPROPANES: TWO REVISED STRUCTURES

1-(2',4'-dihydroxy-3',5'-dimethylphenyl)-3-(2"-hydroxy-4",5"-methylenedioxyphenyl)-Propane, isolated from Iryanthera coriacea and I. laevis, 1-(2'-hydroxy-4'-methoxy-5'-methylphenyl)-3-(2"-hydroxy-4",5"-methylene-dioxyphenyl)-propane, isolated from I. laevis, and 1-(2'-hydroxy-4'-methoxyphenyl)-3-(3"-hydroxy-4"-methoxyphenyl)-propane, isolated from Virola multinervia, were synthesized by processes which involved catalityc hydrogenation of the appropriate chalcones and Clemmensen reduction of dihydrochalcones.Only the structures of 1,3-diarylpropanes isolated from V. multinervia and I. laevis were revised. - Keywords: Virola multinervia; Iryanthera coriaceae; I. laevis; Myristicaceae; 1,3-diarylpropanes; synthesis; reduction of chalcones and dihydrochalcones.