585524-85-2Relevant academic research and scientific papers
Radiosynthesis of SPECT tracers: Via a copper mediated 123I iodination of (hetero)aryl boron reagents
Wilson, Thomas C.,McSweeney, Greg,Preshlock, Sean,Verhoog, Stefan,Tredwell, Matthew,Cailly, Thomas,Gouverneur, Véronique
supporting information, p. 13277 - 13280 (2016/11/17)
A general method for the copper mediated nucleophilic 123I-iodination of (hetero)aryl boronic esters and acids has been developed. The broad substrate scope of this radiosynthetic approach allows access to [123I]DPA-713, [123I]IMPY, [123I]MIBG and [123I]IPEB that are four commonly used SPECT radiotracers. Our results infer that aryl boronic reagents can now be employed as common precursors for both fluorine-18 and iodine-123 radiolabelling.
No-carrier-added radioiodination of triolborates, water-soluble complexes of boronic acids
Akula, Murthy R.,Yao, Min-Liang,Kabalka, George W.
experimental part, p. 132 - 134 (2011/10/12)
A convenient and rapid synthesis of iodine-123 labeled aryl and heteroaryl iodides from water-soluble complexes of aryl- and heteroarylboronic acids has been developed. Copyright
