585526-30-3Relevant academic research and scientific papers
Asymmetric total synthesis of (-)-spirofungin A and (+)-spirofungin B
Shimizu, Takeshi,Satoh, Tomoharu,Murakoshi, Katsunori,Sodeoka, Mikiko
, p. 5573 - 5576 (2007/10/03)
(Chemical Equation Presented) The stereocontrolled total synthesis of (-)-spirofungin A (1) and (+)-spirofungin B (2a), polyketide-type antibiotics having various antifungal activities, has been achieved employing the Weinreb amide 8, the alkyne 9, and th
Efficient synthesis of the 6,6-spiroacetal of spirofungin A
Shimizu, Takeshi,Kusaka, Junichi,Ishiyama, Haruaki,Nakata, Tadashi
, p. 4965 - 4968 (2007/10/03)
The 6,6-spiroacetal segment of spirofungin A, an antifungal antibiotic isolated from Streptomyces violaceusniger Tü 4113, was efficiently prepared via the coupling reaction of the Weinreb amide and the alkyne which are readily available from the common in
