585533-41-1Relevant academic research and scientific papers
One-pot solid phase synthesis of (E)-nitroalkenes
Rokhum, Lalthazuala,Bez, Ghanashyam
, p. 5500 - 5504 (2013/09/23)
An efficient one-pot protocol for the synthesis of (E)-nitroalkenes by reaction of aldehydes and nitroalkanes in the presence of polymer-bound triphenylphosphine, iodine and imidazole is described. Although the reaction works with similar efficiency with triphenylphosphine and its polymer-bound version, easy removal of the unwanted polymer-bound triphenylphosphine oxide and its recovery as triphenylphosphine provide the edge for practical application of the method.
Enantio- and regioselective conjugate addition of organometallic reagents to linear polyconjugated nitroolefins
Tissot, Matthieu,Alexakis, Alexandre
supporting information, p. 11352 - 11363 (2013/09/02)
The copper-catalysed conjugate addition of trialkylaluminium and dialkylzinc reagents to polyconjugated nitroolefins (nitrodiene and nitroenyne derivatives) is reported. A reversed Josiphos ligand L7 allows for the selective 1,4- or 1,6-addition with high enantioselectivities. Copyright
A highly syn-selective nitroaldol reaction catalyzed by Cu II-bisimidazoline
Cheng, Liang,Dong, Jiaxing,You, Jingsong,Gao, Ge,Lan, Jingbo
supporting information; experimental part, p. 6761 - 6765 (2010/08/06)
(Chemical Equation Presented) Catalyzing Henry: Chiral bisimidazoline 1-Cu(OTf)2, in the presence of N-methylmorpholine as a base, was discovered to efficiently catalyze the nitroaldol reaction in a highly syn- and enantioselective manner for a broad range of aldehydes, including aromatic, heteroaromatic, α,β-unsaturated, and aliphatic aldehydes (see scheme).
A heterobimetallic Pd/La/Schiff base complex for anti-selective catalytic asymmetric nitroaldol reactions and applications to short syntheses of β-adrenoceptor agonists
Handa, Shinya,Nagawa, Keita,Sohtome, Yoshihiro,Matsunaga, Shigeki,Shibasaki, Masakatsu
, p. 3230 - 3233 (2008/12/23)
(Chemical Equation Presented) Two metals in a pod: The combination of Pd and La with a dinucleating Schiff base was developed for anti selectivity in the catalytic asymmetric nitroaldol reaction (see scheme). Short syntheses of β-adrenoceptor agonists by using the heterobimetallic catalyst are presented.
