58557-63-4 Usage
Uses
Used in Organic Synthesis:
2-Amino-7-bromo-9-fluorenone is used as a building block for the synthesis of other organic compounds, contributing to the creation of a diverse range of chemical products.
Used in Organic Chemistry Reactions:
As a reagent, 2-Amino-7-bromo-9-fluorenone plays a crucial role in facilitating various organic chemistry reactions, aiding in the formation of desired products.
Used in Pharmaceutical Research and Development:
In the pharmaceutical industry, 2-Amino-7-bromo-9-fluorenone is utilized in the research and development of new drugs, potentially leading to the discovery of novel therapeutic agents.
Used in Agrochemical Research and Development:
2-AMINO-7-BROMO-9-FLUORENONE is also employed in the agrochemical sector for the development of new pesticides and other agricultural chemicals, enhancing crop protection and yield.
Used in Specialty Chemicals Research and Development:
2-Amino-7-bromo-9-fluorenone contributes to the advancement of specialty chemicals, which are used in specific applications across various industries.
Used in Materials Science:
With potential applications in materials science, 2-AMINO-7-BROMO-9-FLUORENONE may be instrumental in the development of new materials with unique properties.
Used as a Fluorescent Dye in Biological Imaging and Microscopy:
2-Amino-7-bromo-9-fluorenone serves as a fluorescent dye in biological imaging and microscopy, aiding researchers in visualizing cellular structures and processes with enhanced clarity and precision.
Check Digit Verification of cas no
The CAS Registry Mumber 58557-63-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,8,5,5 and 7 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 58557-63:
(7*5)+(6*8)+(5*5)+(4*5)+(3*7)+(2*6)+(1*3)=164
164 % 10 = 4
So 58557-63-4 is a valid CAS Registry Number.
InChI:InChI=1/C13H8BrNO/c14-7-1-3-9-10-4-2-8(15)6-12(10)13(16)11(9)5-7/h1-6H,15H2
58557-63-4Relevant academic research and scientific papers
COMPOSITIONS AND METHODS OF MAKING EXPANDED HEMATOPOIETIC STEM CELLS USING DERIVATIVES OF FLUORENE
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Paragraph 0395; 0396, (2019/05/15)
This invention is directed to, inter alia, compounds, methods, systems, and compositions for the maintenance, enhancement, and expansion of hematopoietic stem cells derived from one or more sources of CD34+ cells. Sources of CD34+ cells include bone marrow, cord blood, mobilized peripheral blood, and non-mobilized peripheral blood. Also provided herein are compounds of Formula I which are useful in maintaining, enhancing, and expanding of hematopoietic stem cells.
Synthesis and radiofluorination of novel fluoren-9-one based derivatives for the imaging of α7 nicotinic acetylcholine receptor with PET
Teodoro, Rodrigo,Scheunemann, Matthias,Wenzel, Barbara,Peters, Dan,Deuther-Conrad, Winnie,Brust, Peter
supporting information, p. 1471 - 1475 (2018/04/10)
By structure–activity relationship studies on the tilorone scaffold, the ‘one armed’ substituted dibenzothiophenes and the fluoren-9-ones were identified as the most potential α7 nAChR ligands. While the suitability of dibenzothiophene derivatives as PET tracers is recognized, the potential of fluoren-9-ones is insufficiently investigated. We herein report on a series of fluoren-9-one based derivatives targeting α7 nAChR with compounds 8a and 8c possessing the highest affinity and selectivity. Accordingly, with [18F]8a and [18F]8c we designed and initially evaluated the first fluoren-9-one derived α7 nAChR selective PET ligands. A future application of these radioligands is facilitated by the herein presented successful implementation of fully automated radiosynthesis.
