58570-32-4

Basic information

• Product Name: 1-(chloromethylene)hexahydro-1H-azepinium chloride
• Synonyms: 1-(chloromethylene)hexahydro-1H-azepinium chloride
• CAS NO: 58570-32-4
• Molecular Formula: C₇H₁₃ClN*Cl
• Molecular Weight: 182.09082
• EINECS: 261-336-3
• Mol File: 58570-32-4.mol
• Article Data: 3

Chemical Properties

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: g/cm³
• CAS DataBase Reference: 1-(chloromethylene)hexahydro-1H-azepinium chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(chloromethylene)hexahydro-1H-azepinium chloride(58570-32-4)
• EPA Substance Registry System: 1-(chloromethylene)hexahydro-1H-azepinium chloride(58570-32-4)

Safety Data

• Hazardous Substances Data: 58570-32-4(Hazardous Substances Data)

Usage

General Description

1-(chloromethylene)hexahydro-1H-azepinium chloride is a chemical compound with the molecular formula C7H14ClN. It is a quaternary ammonium salt with a positively charged nitrogen atom and a chloride ion as the counterion. 1-(chloromethylene)hexahydro-1H-azepinium chloride is often used as a reactant in organic synthesis and can also be used in medicinal chemistry as a building block for the synthesis of various pharmaceuticals and biologically active compounds. The presence of the chloromethylene group makes this compound a useful intermediate in the production of heterocyclic compounds and can participate in a variety of chemical reactions, making it a versatile and valuable compound in the field of organic chemistry.

InChI:InChI=1/C7H13ClN.ClH/c8-7-9-5-3-1-2-4-6-9;/h7H,1-6H2;1H/q+1;/p-1

Upstream product

• 111-49-9 hexamethylene imine 
• 75-87-6 chloral 
• 4732-69-8 Chloro-oxo-acetic acid 
• 109-94-4 formic acid ethyl ester 
• 25114-81-2 N-formylhexamethyleneimine 

Downstream Products

• 63699-71-8 1'S-bacmecillinam hydrochloride 
• 63699-71-8 1'R-bacmecillinam hydrochloride 

Relevant articles and documents

6-amido-1-methyl carbapenems

New antibacterial 6-amido-1-methylcarbapenems and process for their synthesis involving new azetidinone intermediates.

Bis-penicillanoyloxy-alkanes

The present invention relates to hitherto unknown esters of the below formula I, to salts of the esters of formula I with pharmaceutically acceptable acids, to methods for producing said new compounds, to pharmaceutical compositions containing said new compounds, and to methods of treating patients suffering from infectious diseases using said new compounds. The compounds of the invention, which are valuable in the human and veterinary practice, have the formula I STR1 in which R1 and R2 represent the same or different substituents, and each represents hydrogen or lower alkyl; A represents a carbon chain having from 5 to 8 carbon atoms, in which optionally an oxygen or a sulphur atom can be substituted for a methylene group; or the grouping STR2 represents a bicyclic system containing from 5 to 10 carbon atoms, or a bicyclic system containing from 4 to 9 carbon atoms, in which optionally an oxygen or a sulphur atom is substituted for a methylene group; or the grouping STR3 represent a spirocyclic system containing from 7 to 10 carbon atoms; R3 represents hydrogen or lower alkyl, halogen substituted lower alkyl, and unsubstituted and substituted aryl and aralkyl. The esters of the present invention are absorbed efficiently when given orally and are non-toxic when given parenterally. After the absorption the esters are converted to the corresponding penicillanic acids by enzymatic hydrolysis. Furthermore, these esters are chemically more stable then the corresponding free acids.