58576-73-1Relevant articles and documents
Synthesis of glycerolipids containing simple linear acyl chains or aromatic rings and evaluation of their Mincle signaling activity
Matsumaru, Takanori,Ikeno, Risa,Shuchi, Yusuke,Iwamatsu, Toshiki,Tadokoro, Takashi,Yamasaki, Sho,Fujimoto, Yukari,Furukawa, Atsushi,Maenaka, Katsumi
supporting information, p. 711 - 714 (2019/02/06)
Mincle, expressed in activated phagocytes, recognizes the lipid ligand to activate the innate immune system. We have synthesized glycerol derivatives possessing simple alkyl chains or aromatic rings and elucidated their structure-activity relationships us
Porphyrin containing lipophilic amide groups as a photosensitizer for dye-sensitized solar cells
Gasiorowski,Pootrakulchote,Reanprayoon,Jaisabuy,Vanalabhpatana,Sariciftci,Thamyongkit
, p. 72900 - 72906 (2015/09/15)
In this study, synthesis and investigation of a novel zinc-porphyrin derivative bearing C24-containing amide groups for potential use in dye-sensitized solar cells (DSSCs) are presented. According to absorption spectra and electrochemical data, the target porphyrin has appropriate highest occupied molecular orbital (HOMO) and lowest unoccupied molecular orbital (LUMO) energy levels. The device studies revealed that the DSSCs based on the target porphyrin exhibited higher light harvesting efficiency in the Q-band region and an increased photocurrent, compared to the DSSCs based on a benchmark derivative bearing no alkyl amide groups on the meso-phenyl substituents. The optimum DSSC based on the target porphyrin gave a short-circuit photocurrent density (Jsc), an open-circuit voltage (Voc) and a fill factor (FF) of 5.6 mA cm-2, 0.7 V and 0.78, respectively, with an overall power conversion efficiency (PCE) of 3.1%.
Method of preparation of alpha galactosyl ceramides compounds
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Paragraph 0180; 0181, (2014/05/20)
The present invention relates to a method of preparation of α-galactosyl ceramides compounds of formula (I): comprising a step a) of glycosylation of a compound of formula (II): with a compound of formula (III):
METHOD OF PREPARATION OF α-GALACTOSYL CERAMIDES COMPOUNDS
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Page/Page column 30, (2014/05/24)
The present invention relates to a method of preparation of α-galactosyl ceramides compounds of formula (I) comprising a step a) of glycosylation of a compound of formula (II) with a compound of formula (III).
Synthesis and biological evaluation of novel aliphatic amido-quaternary ammonium salts for anticancer chemotherapy: Part i
Yang, Jee Sun,Song, Doona,Lee, Boah,Ko, Won Jin,Park, Song-Kyu,Won, Misun,Lee, Kiho,Kim, Hwan Mook,Han, Gyoonhee
experimental part, p. 2861 - 2866 (2011/06/27)
We synthesized novel aliphatic amido-quaternary ammonium salts in an effort to discover anticancer agents that increase Ras homolog gene family, member B, (RhoB) levels. These compounds exert anti-proliferative activities against several human cancer cell types. Seventeen compounds, varying in aliphatic carbon chain length and N-substituents, were synthesized and their biological activities were evaluated. Of these 17 compounds, compound 3i emerged as the most promising anticancer compound by promoting apoptosis through the RhoB mediated pathway. Potent biological activities observed for these novel aliphatic amido-quaternary ammonium salt analogues support their potential as anticancer, chemotherapeutic agents.
Synthesis and biological activity of α-glucosyl C24:0 and C20:2 ceramides
Jervis, Peter J.,Veerapen, Natacha,Bricard, Gabriel,Cox, Liam R.,Porcelli, Steven A.,Besra, Gurdyal S.
supporting information; experimental part, p. 3475 - 3478 (2010/08/07)
α-Glucosyl ceramides 4 and 5 have been synthesised and evaluated for their ability to stimulate the activation and expansion of human iNKT cells. The key challenge in the synthesis of both target molecules was the stereoselective synthesis of the α-glycos
A WAX ESTER FROM PIPER CLARKII
Boll, Per M.,Hald, Mogens,Parmar, Virinder S.,Tyagi, Om Dutt,Bisht, Kirpal S.,et al.
, p. 1035 - 1037 (2007/10/02)
A novel type of wax ester has been isolated from a petrol extract of stems and leaves of Piper clarkii and its structure established as 3-(4-hydroxyphenyl)propyl tetracosanoate.The structure was verified by synthesis.The oxygenated cyclohexane (+)-crotepoxide and β-sitosterol were also isolated. Key words: Piper clarkii; Piperaceae; wax ester; 3-(4-hydroxyphenyl)propyl tetracosanoate; (+)-crotepoxide.
A CONVENIENT SYNTHESIS OF 1-TRIACONTANOL
Rama Rao, A. V.,Deshmukh, M. N.,Kamalam, M.
, p. 227 - 230 (2007/10/02)
1-Triacontanol, a new plant growth regulator, has been synthesised starting from stearic acid, and by two successive additions of six carbon units through enamine intermediates.
