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Relevant academic research and scientific papers

Palladium-Catalyzed Iodofluorination of Alkenes Using Fluoro-Iodoxole Reagent

The application of an air- and moisture-stable fluoroiodane reagent was investigated in the palladium-catalyzed iodofluorination reaction of alkenes. Both the iodo and fluoro substituents arise from the fluoroiodane reagent. In the case of certain palladi

Halofluorination of alkenes using trihaloisocyanuric acids and HF-pyridine

Halofluorination of alkenes with a new system (trihaloisocyanuric acids and HF-pyridine) results in the formation of vicinal halofluoroalkanes. The reaction is regioselective leading to Markovnikov-oriented products and the halofluorinated adducts follow anti-addition in the case of cyclohexene and 1-methylcyclohexene. Reaction yields range from 67-88%. Georg Thieme Verlag Stuttgart · New York.

Fluorination with ionic liquid EMIMF(HF)2.3 as mild HF source

Hydrogen fluoride is a basic fluorinating reagent, but handling it is difficult. For this reason, some modified fluorinating reagents such as HF-pyridine, Et3N-HF, and poly(hydrogen fluoride) complex have been developed. Those reagents, however, still require aqueous work-up procedures which generate hydrogen fluoride. Recently, ionic liquids have received much attention because of the ease in handling them and the possibility of non-aqueous work-up. An ionic liquid, 3-ethyl-1-methyimidazolium oligo hydrogen fluoride (EMIMF(HF)2.3), which is stable in air and moisture, can be used as a hydrogen fluoride equivalent for some fluorination reactions; it does not require an aqueous work-up.

A mild method for halofluorination of alkenes with ionic liquid EMIMF(HF)2.3

Halofluorination of alkene in the presence of N-halosuccinimide and ionic liquid, 3-ethyl-1-methyl-imidazorium oligo hydrogen fluoride (EMIMF(HF) 2.3), as a HF source was demonstrated. Various alkenes were converted into β-halo organofluorides

Halofluorination of alkenes with ionic liquid EMIMF(HF)2.3

Halofluorination of alkene by means of N-halosuccinimide and ionic liquid, 1-ethyl-3-methylimidazorium oligo hydrogenfluoride (EMIMF(HF)2.3), was demonstrated. Various alkenes were converted into β-halo organofluorides in good yields after non-

Halofluorination of Alkenes Using Dilute Hydrofluoric Acid

Iodofluorination of alkenes was achieved with N-iodosuccinimide, potassium hydrogendifluoride, and 1 M hydrofluoric acid using tetrabutylammonium fluoride as a phase-transfer catalyst.The active fluorinating reagent was shown to be tetrabutylammonium dihy

Potassium fluoride-poly(hydrogen fluoride) salts as fluorinating agents for halofluorination of alkenes

It was found that potassium fluoride-poly(hydrogen fluoride) salts are useful fluorine sources for halofluorination of alkenes. The reaction proceeded with these salts and N-halosuccinimides or 1,3-dibromo-5,5-dimethylhydantoin in a regio- and stereoselec

Selective Halofluorination of Alkenes with Tetrabutylphosphonium Dihydrogentrifluoride in Combination with N-Halosuccinimide or 1,3-Dibromo-5,5-dimethylhydantoin

Alkenes and their functionalized derivatives were readily converted to the corresponding halofluorides with tetrabutylphosphonium dihydrogentrifluoride as combined with N-halosuccinimides or 1,3-dibromo-5,5-dimethylhydantoin in highly regio-, stereo-, and

Halofluorination of Alkenes Using Tetrabutylammonium Dihydrogentrifluoride

Regio-, stereo-, and chemoselective halofluorination of alkenes is achieved using N-haloamides and tetrabutylammonium dihydrogentrifluoride, and the resulting F-I adducts were successfully converted into fluoroalkenes under dehydroiodation with 1,8-diazab

Selective Halofluorination Reaction Mediated by Hexafluoropropene-Diethylamine Complex and N-Haloimides

Olefins were halofluorinated with hexafluoropropene-diethylamine and N-haloimides in a highly regio- and stereoselective manner.