58624-00-3Relevant academic research and scientific papers
Iron-catalyzed chemo- and stereoselective hydromagnesiation of diarylalkynes and diynes
Ilies, Laurean,Yoshida, Takumi,Nakamura, Eiichi
supporting information, p. 16951 - 16954,4 (2020/09/02)
Diarylalkynes are chemo- and stereoselectively hydromagnesiated in high yields at room temperature with an iron species generated in situ from FeCl 2and EtMgBr. Functional groups such as bromide, iodide, amine, phenoxide, and alkene are well tolerated. Under similar conditions, diynes are chemo-, regio-, and stereoselectively hydromagnesiated. The resulting alkenylmagnesium compounds are a platform for further functionalization as a one-pot reaction.
