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GLUTARYL-PHE-AMC, also known as Glutaryl-L-phenylalanine 7-Amido-4-methylcoumarin, is a sensitive fluorogenic substrate specifically designed for the detection and measurement of chymotrypsin activity. It is a synthetic peptide derivative that, upon enzymatic cleavage by chymotrypsin, releases a fluorescent product, allowing for the quantification of enzyme activity in various experimental setups.

58632-47-6

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58632-47-6 Usage

Uses

Used in Research and Diagnostic Applications:
GLUTARYL-PHE-AMC is used as a substrate for chymotrypsin in research and diagnostic applications to study the activity and function of this serine protease enzyme. The released fluorescent product allows for the sensitive and accurate measurement of chymotrypsin activity, which is crucial in understanding its role in various biological processes and disease states.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, GLUTARYL-PHE-AMC is used as a tool for the development and optimization of chymotrypsin inhibitors. These inhibitors can be potential therapeutic agents for conditions where chymotrypsin activity is dysregulated, such as certain inflammatory diseases and cancer.
Used in Quality Control:
GLUTARYL-PHE-AMC is also utilized in the quality control of chymotrypsin preparations, ensuring the purity and potency of the enzyme in commercial products. The substrate's sensitivity and specificity make it an ideal choice for assessing the performance of chymotrypsin in various formulations and applications.

Check Digit Verification of cas no

The CAS Registry Mumber 58632-47-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,8,6,3 and 2 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 58632-47:
(7*5)+(6*8)+(5*6)+(4*3)+(3*2)+(2*4)+(1*7)=146
146 % 10 = 6
So 58632-47-6 is a valid CAS Registry Number.
InChI:InChI=1/C24H24N2O6/c1-15-12-23(30)32-20-14-17(10-11-18(15)20)25-24(31)19(13-16-6-3-2-4-7-16)26-21(27)8-5-9-22(28)29/h2-4,6-7,10-12,14,19H,5,8-9,13H2,1H3,(H,25,31)(H,26,27)(H,28,29)

58632-47-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name Glutaryl-L-phenylalanine 7-amido-4-methylcoumarin

1.2 Other means of identification

Product number -
Other names GLUTARYL-PHE-AMC

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:58632-47-6 SDS

58632-47-6Upstream product

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