58634-53-0 Usage
Description
4,6-bis[(benzyloxy)amino]-5,6-dihydropyrimidin-2(1H)-one, also known as Compound JNJ 7777120, is a chemical compound belonging to the class of dihydropyrimidines. It is characterized by its potent and selective antagonism of the histamine H4 receptor, which plays a crucial role in the regulation of inflammation and immune responses. This unique chemical structure and its binding properties position it as a promising candidate for the development of new drugs targeting the histamine H4 receptor, with potential therapeutic applications in the treatment of inflammatory and allergic diseases.
Uses
Used in Pharmaceutical Industry:
4,6-bis[(benzyloxy)amino]-5,6-dihydropyrimidin-2(1H)-one is used as a therapeutic agent for the treatment of inflammatory and allergic diseases. Its action as a histamine H4 receptor antagonist allows it to modulate immune responses and potentially alleviate symptoms associated with these conditions.
Used in Drug Development Research:
In the field of drug development, 4,6-bis[(benzyloxy)amino]-5,6-dihydropyrimidin-2(1H)-one serves as a key compound for research into the histamine H4 receptor's role in inflammation and immune regulation. This research is vital for understanding the pharmacological mechanisms and exploring the potential clinical applications of this compound and similar antagonists.
Further research is necessary to fully elucidate the pharmacological mechanisms of 4,6-bis[(benzyloxy)amino]-5,6-dihydropyrimidin-2(1H)-one and to assess its safety and efficacy in clinical settings. This will ultimately determine its suitability as a new drug for the treatment of inflammatory and allergic diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 58634-53-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,8,6,3 and 4 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 58634-53:
(7*5)+(6*8)+(5*6)+(4*3)+(3*4)+(2*5)+(1*3)=150
150 % 10 = 0
So 58634-53-0 is a valid CAS Registry Number.