58643-70-2Relevant academic research and scientific papers
METHOD FOR PRODUCING 3-METHYL CYCLOPENTADECENONES
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Paragraph 0047-0051, (2017/12/01)
PROBLEM TO BE SOLVED: To provide a method for producing 3-methyl cyclopentadecenones in which the 3-methyl cyclopentadecenones can efficiently be produced. SOLUTION: The 3-methylcyclopentadecenones is produced by an intramolecular condensation reaction of 2,15-hexadecanedione represented by the chemical formula of CH3CO(CH2)12 COCH3. And, in the intramolecular condensation reaction, by using a catalyst having a BET specific surface area of 10 m2/g or less, a decrease in yield due to an increase of the intermolecular condensation reaction on the catalyst can be suppressed as well as, because the deterioration of catalyst can be suppressed, 3-methylcyclopentadecenones can efficiently be produced by the intramolecular condensation reaction. Further, the catalyst is preferably at least one of magnesium oxide, calcium oxide and zinc oxide. SELECTED DRAWING: None COPYRIGHT: (C)2017,JPOandINPIT
Direct, practical, and powerful crossed aldol additions between ketones and ketones or aldehydes utilizing environmentally benign TiCl4-Bu3N reagent
Tanabe, Yoo,Matsumoto, Noriaki,Higashi, Takahiro,Misaki, Tomonori,Itoh, Tomotaka,Yamamoto, Misako,Mitarai, Kumi,Nishii, Yoshinori
, p. 8269 - 8280 (2007/10/03)
An efficient TiCl4-Bu3N - (cat. TMSCl)-promoted aldol addition between ketones and ketones or aldehydes was performed. This environmentally benign method is advantageous from a green chemical viewpoint with regard to yield, substrate
92. A Short Synthesis of (+/-)-Muscone
Rautenstrauch, Valentin,Snowden, Roger L.,Linder, Simon M.
, p. 896 - 901 (2007/10/02)
(+/-)-Muscone ((+/-)-1) has been synthesized in three steps from 2-(2'-methylprop-2'-enyl)cyclododecan-1-one (2).The synthesis involves two key transformations: a Lewis-acid-mediated intramolecular ene reaction (2 -> 3) and the β-cleavage of the bicyclic potassium alkoxide 3a' to the macrocyclic enone (Z)-11.
