58645-50-4

Usage

Uses

Used in Pharmaceutical Synthesis:
1-(2-METHOXYPHENYL)-2-NITROPROPENE is used as an intermediate in the synthesis of various pharmaceuticals and organic compounds. Its unique chemical structure allows it to be a valuable building block for the development of new drugs and other organic molecules.
Used in Chemical Research:
In the field of chemical research, 1-(2-METHOXYPHENYL)-2-NITROPROPENE is utilized as a precursor for the synthesis of complex organic molecules. Its reactivity and functional groups make it a useful compound for exploring new chemical reactions and developing novel synthetic pathways.
Used in Illicit Substance Production (with caution):

InChI:InChI=1/C10H11NO3/c1-8(11(12)13)7-9-5-3-4-6-10(9)14-2/h3-7H,1-2H3/b8-7+

Upstream product

• 79-24-3 Nitroethane 
• 135-02-4 ortho-anisaldehyde 
• 100137-54-0 1-acetoxy-1-(2-methoxy-phenyl)-2-nitro-propane 

Downstream Products

• 5211-62-1 1-(2-methoxyphenyl)propan-2-one 
• 116272-93-6 (2S,3R)-3-(2-Methoxy-phenyl)-4-methyl-1-oxy-2-phenyl-2,3-dihydro-azete-2-carboxylic acid diethylamide 
• 1071023-32-9 (E)-N-(1-(2-methoxyphenyl)prop-1-en-2-yl)acetamide 
• 1426079-96-0 2-(2-methoxyphenyl)-3-methylimidazo[1,2-a]pyridine 
• 93-30-1 (-)-[2-(2-methoxy-phenyl)-1-methyl-ethyl]-methyl-amine 
• 93-30-1 (+)-[2-(2-methoxy-phenyl)-1-methyl-ethyl]-methyl-amine 
• 47302-54-5 bis-[2-(2-methoxy-phenyl)-1-methyl-ethyl]-amine 
• 109475-04-9 [2-(2-methoxy-phenyl)-1-methyl-ethyl]-[2]thienylmethyl-amine 
• 101104-91-0 furfuryl-[2-(2-methoxy-phenyl)-1-methyl-ethyl]-amine 
• 93-30-1 methoxyphenamine 
• 865376-68-7 2,5-dimethyl-4-(2-methoxyphenyl)furan-3-carboxylic acid ethyl ester 
• 34322-76-4 1-(2'-methoxyphenyl)-2-nitropropane 

Relevant academic research and scientific papers

Design of phosphorus ligands with deep chiral pockets: Practical Synthesis of chiral β-arylamines by asymmetric hydrogenation

WingPhos, a C2-symmetric bisphosphorus ligand with a deep and well-defined chiral pocket was developed. It has shown high efficiency in the rhodium-catalyzed asymmetric hydrogenation of (E)-β-aryl-N-acetyl enamides, cyclic β-aryl enamides, and heterocyclic β-aryl enamides. A series of chiral β-arylisopropylamines, 2-aminotetralines, and 3-aminochromans can be synthesized with excellent ee values (nbd=3,5-norbornadiene; TON=turnover number). Copyright

An efficient synthesis of (E)-nitroalkenes catalyzed by recoverable diamino-functionalized mesostructured polymers

A clean, efficient, and simple method has been developed for synthesis of (E)-nitroalkenes using FDU-ED as an efficient catalyst. The reactions proceeded with moderate to high yields (60-96%) under mild conditions. The catalyst FDU-ED is recyclable and can be reused more than seven times without significant loss of activity and selectivity.

Asymmetric reduction of nitroalkenes with baker's yeast

Various α,β-disubstituted and trisubstituted nitroalkenes were chemoselectively reduced with baker's yeast to the corresponding nitroalkanes. Stereoselectivities of the reduction of α,β-disubstituted nitroalkenes were modest to low, and e.e.s up to 52% were obtained. Trisubstituted nitroalkenes could be reduced to the corresponding nitroalkanes with excellent enantioselectivities, moderate diastereoselectivities and in good yield.

HENRY CONDENSATION UNDER HIGH PRESSURE. 2. EFFECT OF AROMATIC ALDEHYDE TYPE AND PRESSURE ON THE YIELD OF ω-NITROSTYRENES AND SECONDARY PROCESSES

Condensation of aromatic aldehydes (I)-(XX) with EtNO2 and n-PrNO2 in AcOH in the presence of AcONH4 or i-BuNH2 gives primarily ω-nitrostyrenes (Ia, b) - (XXa, b) and small quantities of nitriles (Ic) - (XXc), oximes (Id) - (XXd), and ketones (Ie, f) - (XXe, f).The yields of (Ia, b) - (XXa, b) at P = 1 atm are higher for acceptor substitutents on the aromatic ring whereas at P = 10 kbar, they are higher for donor substituents.High pressures suppress the formation of (Ic-f) - (XXc-f) and the Z-isomers of (Ia, b) - (XXa, b).The high pressure technique is especially useful in the preparation of donor-substituted (Ia, b) - (XXa, b) which are intermediates in the synthesis of the psychotropic β-phenylethylamines.