58670-93-2

Basic information

• Product Name: N-hydroxymephentermine
• Synonyms: N-hydroxymephentermine;N-Methyl-N-(1,1-dimethyl-2-phenylethyl)hydroxylamine;N-methyl-N-(2-methyl-1-phenylpropan-2-yl)hydroxylamine
• CAS NO: 58670-93-2
• Molecular Formula: C11H17 N O
• Molecular Weight: 179.26
• Mol File: 58670-93-2.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 285.1°Cat760mmHg
• Flash Point: 126.9°C
• Appearance: /
• Density: 1.015g/cm³
• Vapor Pressure: 0.00134mmHg at 25°C
• Refractive Index: 1.534
• CAS DataBase Reference: N-hydroxymephentermine(CAS DataBase Reference)
• NIST Chemistry Reference: N-hydroxymephentermine(58670-93-2)
• EPA Substance Registry System: N-hydroxymephentermine(58670-93-2)

Safety Data

• Hazardous Substances Data: 58670-93-2(Hazardous Substances Data)

Usage

InChI:InChI=1/C11H17NO/c1-11(2,12(3)13)9-10-7-5-4-6-8-10/h4-8,13H,9H2,1-3H3

Upstream product

• 100-92-5 mephentermine 

Relevant articles and documents

The identification and analysis of the metabolic products of mephentermine

Phentermine (Ib), N hydroxymephentermine (Ic) and N hydroxyphentermine (Id) were identified as metabolic products after in vitro incubation of mephentermine (Ia) with rabbit liver microsomal fractions. Compounds Ia, Ib and Ic were also identified as excretion products in the urine of a human subject given a single dose of mephentermine (Ia) sulphate. Derivatization with acetic anhydride, trifluoroacetic anhydride and the trimethylsilyl donor reagent N,O bis(trimethylsilyl) trifluoroacetamide (BSTFA) or hexamethyldisilazane (HMDS) were used for qualitative identification of the metabolic products Ib Id by g.l.c. mass spectrometry and for quantitative determination of Ia Id after extraction from rabbit hepatic homogenates. The synthesis of N hydroxymephentermine (Ic) and the properties of the metabolic products are reported.