58679-57-5

Basic information

• Product Name: Furan, 2-[(trifluoromethyl)thio]-
• CAS NO: 58679-57-5
• Molecular Formula: C5H3F3OS
• Molecular Weight: 168.139
• Mol File: 58679-57-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Furan, 2-[(trifluoromethyl)thio]-(CAS DataBase Reference)
• NIST Chemistry Reference: Furan, 2-[(trifluoromethyl)thio]-(58679-57-5)
• EPA Substance Registry System: Furan, 2-[(trifluoromethyl)thio]-(58679-57-5)

Safety Data

• Hazardous Substances Data: 58679-57-5(Hazardous Substances Data)

Upstream product

• 110-00-9 furan 
• 421-17-0 Trifluoromethylsulfenyl chloride 

Relevant articles and documents

(PERHALOGENMETHYLTHIO)-HETEROCYCLEN, XV. Saeure- und basekatalysierte Umsetzungen von Furan, Selenophen und Pyridin

In the presence of Lewis acids furan reacts with CF3SCl to form 2-trifluoromethylmercaptofuran 1 in yields of less than 1 percent.The yield is increased to 35 percent, if the reaction is carried out in the presence of pyridine. 2-Methyl-5-chlorofluoromethylmercaptofuran 4b-d were prepared similarly.Oxidation of 1 with m-chloroperbenzoic acid leads to the formation of 2-trifluoromethylsulfinyl- 5 and 2-trifluoromethylsulfonylfuran 6 in low yield.Cyclisation of 2,5-hexanedione in the presence of CFnCl3-nSCl gives 2,5-dimethyl-3-CFnCl3-nS-furan (for n = 3, 7a; n = 2, 7b) and 1-chlorodifluoromethylmercapto-2,5-hexanedione 8 for n = 2.Selenophene reacts with CF3SCl in the presence of SnCl4 to give 2-trifluoromethylmercaptoselenophene 9, which, with the aid of CF3SO3H, can be disubstituted to 2,5-bis(trifluoromethylmercapto)selenophene 10. 3,5-Bis(trifluoromethylmercapto)pyridine 12 can be isolated in small amounts as a byproduct obtained during the syntheses of 3-trifluoromethylmercaptopyridine 11.