5870-29-1 Usage
Uses
Used in Ophthalmology:
Cyclopentolate Hydrochloride is used as a mydriatic for inducing pupil dilation and preventing the eye from accommodating for near vision. It is particularly useful in refraction studies and can be neutralized with pilocarpine nitrate solution for complete recovery within a short period.
Used in Antiviral Applications:
Cyclopentolate Hydrochloride is used as an antiviral agent, although the specific application reason is not provided in the materials.
Used in Pharmaceutical Industry:
Cyclopentolate Hydrochloride is used as a cholinergic receptor antagonist for its ability to inhibit carbachol-induced contraction of isolated human iris sphincter, circular ciliary muscle, and longitudinal ciliary muscle. This makes it a valuable component in the development of medications targeting muscarinic acetylcholine receptors.
Clinical Use
Cyclopentolate Hydrochloride is used only for its effects on the eye, where it acts asa parasympatholytic. When placed in the eye, it quickly producescycloplegia and mydriasis. Its primary field of usefulnessis in refraction studies. Cyclopentolate hydrochloridecan be used, however, as a mydriatic in the management ofiritis, iridocyclitis, keratitis, and choroiditis. Although itdoes not seem to affect intraocular tension significantly, it isbest to be very cautious with patients with high intraocularpressure and with elderly patients with possible unrecognizedglaucomatous changes.
Check Digit Verification of cas no
The CAS Registry Mumber 5870-29-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,8,7 and 0 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 5870-29:
(6*5)+(5*8)+(4*7)+(3*0)+(2*2)+(1*9)=111
111 % 10 = 1
So 5870-29-1 is a valid CAS Registry Number.
InChI:InChI=1/C17H25NO3.ClH/c1-18(2)12-13-21-16(19)15(14-8-4-3-5-9-14)17(20)10-6-7-11-17;/h3-5,8-9,15,20H,6-7,10-13H2,1-2H3;1H
5870-29-1Relevant academic research and scientific papers
Preparation method of cyclopentolate hydrochloride
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Paragraph 0014; 0041, (2017/05/04)
The invention relates to a preparation method of an M-type cholinoceptor blocker cyclopentolate hydrochloride. The preparation method comprises that phenylacetic acid as an initial raw material and cyclopentanone undergoes a reaction to produce 2-(1-hydroxycyclopentyl)-phenylacetic acid (as intermediate 3), the 2-(1-hydroxycyclopentyl)-phenylacetic acid undergoes a replacement reaction and the reaction product undergoes a salification reaction to produce cyclopentolate hydrochloride. The preparation method can be operated simply, is safe and controllable, has low labor protection demands and is suitable for industrial production.
