58722-31-9

Basic information

• Product Name: 4-((4-ethylphenyl)sulfonyl)morpholine
• Synonyms: 4-((4-ethylphenyl)sulfonyl)morpholine
• CAS NO: 58722-31-9
• Molecular Weight: 255.338
• Mol File: 58722-31-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-((4-ethylphenyl)sulfonyl)morpholine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-((4-ethylphenyl)sulfonyl)morpholine(58722-31-9)
• EPA Substance Registry System: 4-((4-ethylphenyl)sulfonyl)morpholine(58722-31-9)

Safety Data

• Hazardous Substances Data: 58722-31-9(Hazardous Substances Data)

Upstream product

• 774-48-1 (diethoxymethyl)benzene 
• 834-67-3 4-((4-bromophenyl)sulfonyl)morpholine 
• 110-91-8 morpholine 

Relevant articles and documents

Site-Selective C-H Functionalization-Sulfination Sequence to Access Aryl Sulfonamides

Aryl sulfinates are precursors to a diverse number of sulfonyl-derived arenes, which are common motifs in pharmaceuticals and agrochemicals. Here, we report a site-selective two-step C-H sulfination sequence via aryl sulfonium salts to access aryl sulfonamides. Combined with site-selective aromatic thianthrenation, an operationally simple one-pot palladium-catalyzed protocol introduces the sulfonyl group using sodium hydroxymethylsulfinate (Rongalite) as a source of SO22-. The hydroxymethyl sulfone intermediate generated from the catalytic process can be employed as a synthetic handle to deliver a variety of sulfonyl-containing compounds.