58722-34-2

Usage

Uses

Used in Pharmaceutical Industry:
1-[4-(PIPERIDINE-1-SULFONYL)-PHENYL]-ETHANONE is used as an intermediate in the synthesis of various pharmaceuticals for its potential role in the development of new drugs. Its unique structure and functional groups contribute to the creation of compounds with specific therapeutic properties.
Used in Agrochemical Industry:
1-[4-(PIPERIDINE-1-SULFONYL)-PHENYL]-ETHANONE is also used as an intermediate in the synthesis of agrochemicals, where it may contribute to the development of new compounds with pesticidal or herbicidal properties, enhancing crop protection and yield.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, 1-[4-(PIPERIDINE-1-SULFONYL)-PHENYL]-ETHANONE serves as a valuable compound for research and development. Its unique structure allows scientists to explore its potential in the treatment of various diseases, leading to the discovery of novel therapeutic agents.

InChI:InChI=1/C13H17NO3S/c1-11(15)12-5-7-13(8-6-12)18(16,17)14-9-3-2-4-10-14/h5-8H,2-4,9-10H2,1H3

Upstream product

• 110-89-4 piperidine 
• 1788-10-9 4-Acetylbenzenesulfonyl chloride 

Downstream Products

• 110820-41-2 1-[4-(piperidine-1-sulfonyl)phenyl]ethanone thiosemicarbazone 
• 845674-27-3 1-[4-(piperidine-1-sulfonyl)phenyl]ethanone phenylthiosemicarbazone 
• 1042947-79-4 C₁₆H₂₂N₂O₃S 
• 1263308-16-2 2-cyano-N'-(1-(4-(piperidine-1-ylsulfonyl)phenyl)ethylidene)acetohydrazide 
• 1352710-88-3 2-cyano-3-(4-hydroxy-3-methoxyphenyl)-N'-(1-(4-(piperidine-1-ylsulfonyl)phenyl)ethylidene)acrylohydrazide 
• 1352710-89-4 2-cyano-3-(4-(dimethylamino)phenyl)-N'-(1-(4-(piperidine-1-ylsulfonyl)phenyl)ethylidene)acrylohydrazide 
• 1352710-90-7 3-(4-chlorophenyl)-2-cyano-N'-(1-(4-(piperidine-1-ylsulfonyl)phenyl)ethylidene)acrylohydrazide 
• 1352710-91-8 6-amino-2-oxo-1-(1-(4-(piperidine-1-ylsulfonyl)phenyl)ethylideneamino)-4-p-tolyl-1,2-dihydropyridine-3,5-dicarbonitrile 
• 1352710-92-9 6-amino-4-(4-hydroxyphenyl)-2-oxo-1-(1-(4-(piperidine-1-ylsulfonyl)phenyl)ethylideneamino)-1,2-dihydropyridine-3,5-dicarbonitrile 
• 1352710-93-0 6-amino-4-(4-methoxyphenyl)-2-oxo-1-(1-(4-(piperidine-1-ylsulfonyl)phenyl)ethylideneamino)-1,2-dihydropyridine-3,5-dicarbonitrile 
• 1352710-94-1 6-amino-4-(4-hydroxy-3-methoxyphenyl)-2-oxo-1-(1-(4-(piperidine-1-ylsulfonyl)phenyl)ethylideneamino)-1,2-dihydropyridine-3,5-dicarbonitrile 
• 1352710-95-2 6-amino-4-(4-(dimethylamino)phenyl)-2-oxo-1-(1-(4-(piperidine-1-ylsulfonyl)phenyl)ethylideneamino)-1,2-dihydropyridine-3,5-dicarbonitrile 
• 1352710-96-3 6-amino-4-(4-chlorophenyl)-2-oxo-1-(1-(4-(piperidine-1-ylsulfonyl)phenyl)ethylideneamino)-1,2-dihydropyridine-3,5-dicarbonitrile 
• 1352710-97-4 2-cyano-3-ethoxy-N'-(1-(4-(piperidine-1-ylsulfonyl)phenyl)ethylidene)acrylohydrazide 

Relevant academic research and scientific papers

Synthesis and structure-activity relationship of aminopyrimidine IKK2 inhibitors

The synthesis and structure-activity relationship of a novel series of aminopyrimidines are exemplified. Results of key compounds from within this series in the E-selectin reporter cell assay are also reported.

AMINOPYRIMIDINE COMPOUNDS AND METHODS OF USE

The invention relates to aminopyrimidine compounds useful for treating diseases mediated by polo-like kinase 1 (Plk1). The invention also relates to the therapeutic use of such aminopyrimidine compounds and compositions thereof in treating disease states associated with abnormal cell growth and unwanted cell proliferation.

Novel antibacterial amide compounds and process means for producing the same

Novel organic amide compounds which are N-[6-[(aminosulfonyl)phenyl]-1,2-dihydro-2-oxonicotinyl]penicillin and cephalosporin type compounds having broad spectrum antibacterial utility are provided by (a) reacting the free amino acid of the appropriate penicillin or cephalosporin or the acid salt or silylated derivative or complex thereof with a reactive derivative of the corresponing N-6-[(aminosulfonyl)phenyl]-1,2-dihydro-2-oxonicotinic acid or (b) reacting the free amino acid 6-aminopenicillanic acid, 7-aminocephalosporanic acid, 7-amino-3-methylceph-3-em-4-carboxylic acid or a related compound or the acid salt or silylated derivative thereof with a reactive derivative of the corresponding D-N-[6-[(aminosulfonyl)phenyl]-1,2-dihydro-2-oxonicotinyl]-2-substituted glycine. Pharmaceutical compositions containing said compounds and methods for treating infections using said compositions are also disclosed.