58732-05-1

Upstream product

• 83-07-8 4-amino-2,3-dimethyl-1-phenylpyrazolin-5-one 
• 95-01-2 2,4-Dihydroxybenzaldehyde 

Relevant academic research and scientific papers

Electrochemical studies of Schiff base compounds derived from antipyrine nucleus in ethanolic buffer solutions

The electrochemical behaviour of Schiff base compounds derived from an antipyrine nucleus was investigated in 30% (v/v) ethanolic buffer solutions (pH 3-11) using various electrochemical techniques at mercury electrode. The results showed that, the total

Antipyrine based Schiff's base as a reversible fluorescence turn “off-on-off” chemosensor for sequential recognition of Al3+ and F? ions: A theoretical and experimental perspective

A Schiff's base probe (L) based on antipyrine has been intended, synthesized and assessed as a turn “off-on-off” probe for successive recognition of Al3+ and F?. The probe L act out as a turn “on” fluorescence probe towards Al3+

Synthesis, characterization, electrochemical studies and antimicrobial activities of metal complexes

Metal complexes of Schiff base 4-[(2, 4-dihydroxy-benzylidene)-amino]-1, 5-dimethyl-2-phenyl-1, 2-dihydroxo-pyrazol-3-one (H2L) derived from condensation of 2,4-dihydroxybenzaldehyde and 4-aminoantipyrine were synthesized and characterized by FT-IR spectra, elemental analysis, 1H &13C NMR, mass spectra, UV–Visible, X-ray diffraction, molar conductance, magnetic moment and thermal analysis (TGA). The elemental analysis proved that the complexes have the general formulae of [M(HL)(X)(OH2)]2, where M = Cu(II); X = OAc?(1); NO3?(2); Cl?(3), M = Co(II) (4), Mn(II) (5); X = OAc and {[UO2(HL)]2.2(OAc)}(6). According to the FT-IR spectra data, it was found that the H2L ligand is coordinated to the metal ions in a tridentate donor sites of the nitrogen atom of azomethine group, the oxygen atom of phenolic group and the oxygen atom of carbonyl group. From the measurements of magnetic susceptibility and electronic spectral data, it is found that these complexes are octahedral geometries. The trend in g value (g║ ? g⊥ ? 2.00) suggests that the unpaired electron on copper has dx2-y2 character and the complexes have an octahedral structure. By comparing the synthesized ligand (H2L) to its metal complexes was screened for their antibacterial activity against Klebsiella pneumoniae, Escherichia coli, Pseudomonas sp., Bacillus cereus and Staphylococcus aureus. It was found that the metal complexes had more potent antimicrobial than the parent Schiff base ligand against one or more microbial species. Some complexes showed higher activity than ligand. The complex (3) has antibacterial activities against Bacillus cereus, Klebsiella pneumoniae and Staphylococcus aureus. The antibacterial activity of complex (3) was the highest ones than the ligand and other complexes as well as penicillin G against Klebsiella pneumoniae. Antifungal activities were determined against Fusarium oxysporum, Aspergillus niger and Candida albicans. The inhibition efficiency of the prepared ligand (H2L) against the corrosion of carbon steel in HCl (2?M) solution was determined by various electrochemical techniques.

Design, crystal structures and sustainable synthesis of family of antipyrine derivatives: Abolish to bacterial and parasitic infection

This work explores the facile synthesis of a series of antipyrine acetylinic framework (3a-3h). The newly synthesized compounds are recognized by IR, NMR (1H, 13C), X-ray diffraction. This collection played indispensable role in the

Preparation of a simple biocompatible magnetite@citric acid: An efficient reusable solid acid catalyst for the rapid synthesis of antipyrine Schiff’s bases and study of their radical scavenging potential

Citric acid immobilized magnetic nanoparticles (MNPs@CA) have been synthesized and used for the preparation of bio-important antipyrine (1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one) derived Schiff’s bases (3a–k) in lesser reaction time with very hi

Synthesis of novel Schiff base analogues of 4-amino-1,5-dimethyl-2- phenylpyrazol-3-one and their evaluation for antioxidant and anti-inflammatory activity

4-Aminoantipyrine (4-amino-1,5-dimethyl-2-phenylpyrazole-3-one) and its analogues have been found to be compounds of interest for their anti-inflammatory, analgesic, antiviral, antipyretic, antirheumatic and antimicrobial activities. In the present study,