5875-06-9

Basic information

• Product Name: Proparacaine hydrochloride
• Synonyms: 2-[(3-amino-4-propoxyphenyl)-oxomethoxy]ethyl-diethylammonium chloride;Proparacaine hydrochloride, >=99%;PROPARACAINE HCL;PROPARACAINE HYDROCHLORIDE;3-amino-4-propoxybenzoicacid2-(diethylamino)ethylesterhydrochloride;alcaine;benzoicacid,3-amino-4-propoxy-,2-(diethylamino)ethylester,hydrochloride;benzoicacid,3-amino-4-propoxy-,2-(diethylamino)ethylester,monohydrochlorid
• CAS NO: 5875-06-9
• Molecular Formula: C16H27ClN2O3
• Molecular Weight: 330.85
• EINECS: 227-541-7
• Mol File: 5875-06-9.mol
• Article Data: 0

Chemical Properties

• Melting Point: 182.0-183.3°
• Boiling Point: 434.4 °C at 760 mmHg
• Flash Point: 216.5 °C
• Appearance: /
• Vapor Pressure: 9.5E-08mmHg at 25°C
• Storage Temp.: Inert atmosphere,Store in freezer, under -20°C
• Solubility: Chloroform (Slightly), Methanol, Water
• PKA: 3.2(at 25℃)
• Merck: 14,7807
• CAS DataBase Reference: Proparacaine hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: Proparacaine hydrochloride(5875-06-9)
• EPA Substance Registry System: Proparacaine hydrochloride(5875-06-9)

Safety Data

• Hazard Codes: Xn
• Statements: 20/21/22-36-43
• Safety Statements: 26-36
• WGK Germany: 3
• RTECS: DG3065000
• Hazardous Substances Data: 5875-06-9(Hazardous Substances Data)

Usage

Uses

Different sources of media describe the Uses of 5875-06-9 differently. You can refer to the following data:
1. Anesthetic;Neuronal conductance inhibitor
2. Topical anesthetic (ophthalmic).

InChI:InChI=1/C16H26N2O3.ClH/c1-4-10-20-15-8-7-13(12-14(15)17)16(19)21-11-9-18(5-2)6-3;/h7-8,12H,4-6,9-11,17H2,1-3H3;1H

Synthetic route

proparacaine hydrochloride (5875-06-9) + calix[6]arene-p-hexasulfonic acid (102088-39-1) → C16H26N2O3*C42H36O24S6

Conditions	Yield
In water at 24.84℃; for 1h;

proparacaine hydrochloride (5875-06-9) + fipronilβ-cyclodextrin (7585-39-9) → β-cyclodextrin (521964-96-5)

Conditions	Yield
In water at 24.84℃; for 1h;

Downstream Products

• 521964-96-5 β-cyclodextrin