58764-87-7Relevant academic research and scientific papers
Silver-catalyzed double-decarboxylative cross-coupling of α-keto acids with cinnamic acids in water: A strategy for the preparation of chalcones
Zhang, Ning,Yang, Daoshan,Wei, Wei,Yuan, Li,Nie, Fafa,Tian, Laijin,Wang, Hua
, p. 3258 - 3263 (2015/03/30)
A silver-catalyzed double-decarboxylative protocol has been proposed for the construction of chalcone derivatives via cascade coupling of substituted α-keto acids with cinnamic acids under the mild aqueous conditions. The developed method for constructing C-C bonds via double-decarboxylative reactions is efficient, practical, and environmentally benign by using the readily available starting materials. It should provide a promising synthesis candidate for the formation of diverse and useful chalcone derivatives in the fields of synthetic and pharmaceutical chemistry.
