58773-45-8

Upstream product

• 501-53-1 benzyl chloroformate 
• 69677-01-6 ((R)-4-Benzyloxycarbonylamino-6-diazo-5-oxo-hexyl)-carbamic acid benzyl ester 
• 69677-00-5 ((R)-4-Benzyloxycarbonylamino-4-chlorocarbonyl-butyl)-carbamic acid benzyl ester 
• 51703-81-2 (3R)-β-lysine 
• 60242-84-4 (R)-N,N-dibenzyloxycarbonyl-β-lysine methyl ester 

Downstream Products

• 60242-85-5 [N'-((R)-3,6-Bis-benzyloxycarbonylamino-hexanoyl)-N-methyl-hydrazino]-acetic acid ethyl ester 
• 69677-17-4 [N'-((R)-3,6-Bis-benzyloxycarbonylamino-hexanoyl)-N-phenyl-hydrazino]-acetic acid 
• 60242-87-7 [N'-((R)-3,6-Bis-benzyloxycarbonylamino-hexanoyl)-N-methyl-hydrazino]-acetic acid 
• 64934-04-9 (R)-3,6-Dibenzyloxycarbonylaminohexanoylsarcosin 
• 69677-16-3 [N'-((R)-3,6-Bis-benzyloxycarbonylamino-hexanoyl)-N-phenyl-hydrazino]-acetic acid ethyl ester 
• 69677-10-7 (R)-3,6-Dibenzyloxycarbonylaminohexanoylsarcosinethylester 
• 83663-06-3 {5-[(2S,4S,5R,6R)-2-Allyloxy-4-hydroxy-6-hydroxymethyl-5-(2-methoxy-ethoxymethoxy)-tetrahydro-pyran-3-ylcarbamoyl]-4-benzyloxycarbonylamino-pentyl}-carbamic acid benzyl ester 

Relevant academic research and scientific papers

Asymmetric Syntheses of the Naturally Ocurring β-Amino Acids, β-Lysine, β-Leucine and β-Phenyl-β-alanine via Nitrone Cycloaddition

A general asymmetric synthesis of β-amino acids is based on the dipolar cycloaddition of nitrones 7 (R* chiral) with vinyl acetate 8a, ketene acetals 8b or α-chloroacrylonitrile 8c.The cycloadducts 9 are converted either directly (9b) or via the isoxazolidones 10 (9a, 9c) into the free β-amino acids 11.Diastereoselectivity at C-3 in the adducts 9 ranges between 2:1 and 11:1.The natural β-amino acids, β-lysine, β-leucine and β-phenyl-β-alanine, have been prepared in this way.