58774-84-8

Basic information

• Product Name: 1-(2-methoxybenzyl)pyrrolidine
• CAS NO: 58774-84-8
• Molecular Formula: C₁₂H₁₇NO
• Molecular Weight: 191.2695
• Mol File: 58774-84-8.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 261.4°C at 760 mmHg
• Flash Point: 76.6°C
• Density: 1.05g/cm³
• Vapor Pressure: 0.0116mmHg at 25°C
• Refractive Index: 1.548
• CAS DataBase Reference: 1-(2-methoxybenzyl)pyrrolidine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-methoxybenzyl)pyrrolidine(58774-84-8)
• EPA Substance Registry System: 1-(2-methoxybenzyl)pyrrolidine(58774-84-8)

Safety Data

• Hazardous Substances Data: 58774-84-8(Hazardous Substances Data)

Upstream product

• 120173-04-8 (2-methoxyphenyl)(pyrrolidin-1-yl)methanone 
• 612-16-8 (2-methoxyphenyl)methanol 
• 609-36-9 rac-Pro-OH 

Relevant articles and documents

Metal-Free Deoxygenation of Amine N-Oxides: Synthetic and Mechanistic Studies

We report herein an unprecedented combination of light and P(III)/P(V) redox cycling for the efficient deoxygenation of aromatic amine N-oxides. Moreover, we discovered that a large variety of aliphatic amine N-oxides can easily be deoxygenated by using only phenylsilane. These practically simple approaches proceed well under metal-free conditions, tolerate many functionalities and are highly chemoselective. Combined experimental and computational studies enabled a deep understanding of factors controlling the reactivity of both aromatic and aliphatic amine N-oxides.

Iridium-catalyzed decarboxylative N-alkylation of α-amino acids with primary alcohols

A new decarboxylative N-alkylation reaction of α-amino acids has been developed. A variety of tertiary amines were obtained in good to excellent yields via the decarboxylative N-alkylation reaction of α-amino acids with primary alcohols catalyzed by a CpIr complex. Georg Thieme Verlag Stuttgart New York.