587878-75-9

Usage

Uses

Used in Organic Synthesis:
Benzamide, 3-ethynyl(9CI) is utilized as a key building block in organic synthesis for the creation of a variety of biologically active compounds. Its unique structure allows for the development of new molecules with potential applications across different fields.
Used in Pharmaceutical Research:
In the pharmaceutical industry, Benzamide, 3-ethynyl(9CI) serves as an essential component in research aimed at discovering and developing new drugs and pharmaceuticals. Its ethynyl group and benzamide core contribute to the design and synthesis of novel therapeutic agents.
Used as a Reagent in Chemical Reactions:
Benzamide, 3-ethynyl(9CI) may also be employed as a reagent in chemical reactions that involve the formation of new carbon-carbon and carbon-nitrogen bonds. This application is crucial for advancing chemical research and the synthesis of complex organic molecules.
While the specific uses of Benzamide, 3-ethynyl(9CI) may vary depending on the context, its versatility in organic synthesis, pharmaceutical research, and as a reagent in chemical reactions highlights its importance in the development of new chemical entities and therapeutic agents.

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Relevant academic research and scientific papers

Pyrtriazoles, a Novel Class of Store-Operated Calcium Entry Modulators: Discovery, Biological Profiling, and in Vivo Proof-of-Concept Efficacy in Acute Pancreatitis

In recent years, channels that mediate store-operated calcium entry (SOCE, i.e., the ability of cells to sense a decrease in endoplasmic reticulum luminal calcium and induce calcium entry across the plasma membrane) have been associated with a number of d

ALKYNYL PHOSPHINE GOLD COMPLEXES FOR TREATING BACTERIAL INFECTIONS

A compound of formula (I) for use in the prevention or treatment of a bacterial infection.

NOVEL CONDENSED PYRAZOLE DERIVATIVE AND MEDICAL USES THEREOF

PROBLEM TO BE SOLVED: To provide a preventive or therapeutic agent for mood disorder, anxiety disorder, schizophrenia, dementia, drug dependence or the like related to subtypes of metabolism type glutamate receptor (mGlu) 2 and 3. SOLUTION: There are prov

Design, Synthesis, and Evaluation of Triazole Derivatives That Induce Nrf2 Dependent Gene Products and Inhibit the Keap1-Nrf2 Protein-Protein Interaction

The transcription factor Nrf2 regulates the expression of a large network of cytoprotective and metabolic enzymes and proteins. Compounds that directly and reversibly inhibit the interaction between Nrf2 and its main negative regulator Keap1 are potential pharmacological agents for a range of disease types including neurodegenerative conditions and cancer. We describe the development of a series of 1,4-diphenyl-1,2,3-triazole compounds that inhibit the Nrf2-Keap1 protein-protein interaction (PPI) in vitro and in live cells and up-regulate the expression of Nrf2-dependent gene products.

PYRROLO[2,3-D]PYRIMIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS KINASE INHIBITORS

The present invention relates to 6-amino-7-deaza-purine derivatives which modulate the activity of protein kinases and are therefore useful in treating diseases caused by dysregulated protein kinase activity, in particular RET family kinases. The present

FAK AND FLT3 INHIBITORS

The use of a compound of the formula (I): (Formula (I)) in the preparation of a medicament for treating Acute Myeloid Leukemia or a disease ameliorated by the inhibition of Flt3, or Flt3 and FAK.

FAK INHIBITORS

A compound of the formula (I): where R1 or R2 is a cycle amine group and R5 is an aromatic group with a carbonyl containing substituent for use as a FAK inhibitor.

Rapid microwave promoted Sonogashira coupling reactions on solid phase

A microwave-enhanced, rapid, and efficient solid-phase version of the Sonogashira reaction is presented. It has been applied to the coupling of aryl iodides and bromides with various acetylene derivatives giving excellent yields in 15-25 min. The scopes of homogeneous, solventless, and solid-phase conditions for Sonogashira coupling of aryl halides are compared.