587885-44-7Relevant articles and documents
The role of fluorine in the stereoselective tandem aza-Michael addition to acrylamide acceptors: An experimental and theoretical mechanistic study
Fustero, Santos,Chiva, Gema,Piera, Julio,Volonterio, Alessandro,Zanda, Matteo,Gonzalez, Javier,Ramallal, Antonio Moran
, p. 8530 - 8542 (2008/04/01)
Aza-Michael additions of αamino esters to fluorinated acceptors take place in a highly stereoselective manner, to give partially modified ψNHCH2]retropeptides incorporating a hydrolytically stable trifluoroalanine mimic. The reaction mechanism